A number of neurodegenerative diseases are accompanied by disordered smell function.
The degree of dysfunction can vary among different diseases, such that olfactory testing can …

The ability of abnormal TSE-associated forms of PrP to seed the formation of amyloid fibrils
from recombinant PrPSen has served as the basis for several relatively rapid and highly …

Olfactory deficits are present in numerous neurodegenerative disorders and are
accompanied by pathology in related brain regions. In several of these disorders, olfactory …

Background Definite diagnosis of sporadic Creutzfeldt–Jakob disease in living patients
remains a challenge. A test that detects the specific marker for Creutzfeldt–Jakob disease …

The minimum infectious dose required to induce CWD infection in cervids remains unknown,
as does whether peripherally shed prions and/or multiple low dose exposures are important …

Chronic wasting disease (CWD), a transmissible spongiform encephalopathy of cervids, was
first documented nearly 50 years ago in Colorado and Wyoming and has since spread to …

Prion diseases are sub-acute neurodegenerative diseases that affect humans and some
domestic and free-ranging animals. Infectious prion agents are considered to comprise …

Chronic wasting disease (CWD), a transmissible spongiform encephalopathy of cervids, was
first documented nearly 50 years ago in Colorado and Wyoming and has since been …

Prion diseases of cattle include the classical bovine spongiform encephalopathy (C-BSE)
and the atypical H-type BSE (H-BSE) and L-type BSE (L-BSE) strains. Although the C-and L …

Prion diseases or transmissible spongiform encephalopathies are a unique category of
infectious protein-misfolding neurodegenerative disorders. Hypothesized to be caused by …