Advancements in microfluidics for skin cosmetic screening

N Hu, K Cheng, S Zhang, S Liu, L Wang, X Du, Y Li… - Analyst, 2023 - pubs.rsc.org
With the global penetration of skin care awareness and upgrading of personal care
awareness, the use rate of cosmetics and personal skin care products has been increasing …

Chitosan-based buccal mucoadhesive patches to enhance the systemic bioavailability of tizanidine

MD Arpa, NÜ Okur, MK Gök, S Özgümüş… - International Journal of …, 2023 - Elsevier
Tizanidine hydrochloride (TZN) is a muscle relaxant used to treat a variety of disorders such
as painful muscle spasms and chronic spasticity. TZN has low oral bioavailability due to …

The formulation and evaluation of deep eutectic vehicles for the topical delivery of azelaic acid for acne treatment

DK Luhaibi, HHM Ali, I Al-Ani, N Shalan, F Al-Akayleh… - Molecules, 2023 - mdpi.com
The current work was aimed at the development of a topical drug delivery system for azelaic
acid (AzA) for acne treatment. The systems tested for this purpose were deep eutectic …

Novel benzydamine hydrochloride and chlorhexidine gluconate loaded bioadhesive films for local treatment of buccal infections

MD Arpa, AP Yağcılar, SN Biltekin - Journal of Drug Delivery Science and …, 2023 - Elsevier
Benzydamine hydrochloride (BZD), chlorhexidine gluconate (CHG) or their combination are
frequently used as liquid dosage forms for the local treatment of buccal fungal and bacterial …

Novel Sprayable Thermosensitive Benzydamine Hydrogels for Topical Application: Development, Characterization, and In Vitro Biological Activities

MD Arpa, EE Kesmen, SN Biltekin - AAPS PharmSciTech, 2023 - Springer
Benzydamine hydrochloride (BZD) having analgesic, anesthetic, and anti-inflammatory
effects is used orally or topically in the treatment of disorders such as joint inflammation and …

Ginger essential oil-loaded hydrogels: preparation, characterization, cytotoxicity, antimicrobial and anti-inflammatory activity

MD Arpa, EE Kesmen, T Arslan… - Journal of Essential …, 2024 - Taylor & Francis
The present study aimed to develop ginger essential oil hydrogel formulations, using sodium
carboxymethyl cellulose (Na CMC), Carbopol, and xanthan gum for dental and oromucosal …

Analysis of drug efficacy for inflammatory skin on an organ-chip system

Q Quan, D Weng, X Li, Q An, Y Yang, B Yu… - … in Bioengineering and …, 2022 - frontiersin.org
Bacterial skin infections cause a variety of common skin diseases that require drugs that are
safer than antibiotics and have fewer side effects. However, for evaluating skin disease …

Novel Microemulsion Containing Benzocaine and Fusidic Acid Simultaneously: Formulation, Characterization, and In Vitro Evaluation for Wound Healing

MD Arpa, EŞ Çağlar, D Güreşçi, H Sipahi… - AAPS …, 2024 - Springer
Modern drug carrier technologies, such as microemulsions with small droplet sizes and high
surface areas, improve the ability of low water solubility active ingredients to permeate and …

[HTML][HTML] Amphiphilic pH-responsive core-shell nanoparticles can increase the performances of cellulose-based drug delivery systems

E Lacroce, G Nunziata, F Cianniello, E Limiti… - International Journal of …, 2024 - Elsevier
Polymer and nanoparticles (NPs) together are able to form nanocomposite materials that
combine the beneficial properties of the traditional single systems. In this work, we propose …

Azelaic acid-based lyotropic liquid crystals gel for acne vulgaris: Formulation optimization, antimicrobial activity and dermatopharmacokinetic study

CM Gowda, S Wairkar - International Journal of Pharmaceutics, 2024 - Elsevier
The proposed study aimed to develop a topical gel containing azelaic acid (AZA)-based
lyotropic liquid crystals (LLCs) for the treatment of acne vulgaris. AZA-based LLCs were …