Ocular drug delivery has been a major challenge to pharmacologists and drug delivery
scientists due to its unique anatomy and physiology. Static barriers (different layers of …

Nanotechnology has been applied in the medicine field to improve the treatment of a wide
range of diseases. However, to reach the nanomedicines delivery to desirable target tissue …

Graft-versus-host disease (GVHD) is a common cause of morbidity and mortality after
allogeneic hematopoietic stem cell transplantation. Systemic findings involving the skin …

This review presents the rationale and supporting data for a recent paradigm shift in our
understanding of meibomian gland dysfunction (MGD). The historical understanding of MGD …

Doxycycline is a member of the tetracycline class of antibiotics and has been used clinically
for more than 40 years. It is a well-tolerated drug that is bacteriostatic and acts via the …

PURPOSE: To describe the cause and consequence of tear dysfunction–related corneal
disease. DESIGN: Perspective on effects of tear dysfunction on the cornea. METHODS …

Neuron–glia interactions play a key role in maintaining and regulating the central nervous
system. Glial cells are implicated in the function of dopamine neurons and regulate their …

Purpose One of the challenges of ocular drug delivery systems is sustainable delivery of the
intended drug to the posterior segment of the eye. Periocular routes of drug delivery are a …

Objective To review the existing medical literature on the role of oral antibiotics in the
management of ocular surface disease (OSD) that arises from disorders of the meibomian …

Purpose: To validate the more easily applicable “flush” tear collection technique as a viable
alternative to basal and reflex tear collection. Materials and Methods: Total protein content …