The role of oxidative stress in pathogenesis and treatment of inflammatory bowel diseases

A Piechota-Polanczyk, J Fichna - Naunyn-Schmiedeberg's archives of …, 2014 - Springer
In this review, we focus on the role of oxidative stress in the aetiology of inflammatory bowel
diseases (IBD) and colitis-associated colorectal cancer and discuss free radicals and free …

Aminosalicylates for induction of remission or response in Crohn's disease

WC Lim, Y Wang, JK MacDonald… - Cochrane Database of …, 2016 - cochranelibrary.com
Background Randomized trials investigating the efficacy of aminosalicylates for the
treatment of mildly to moderately active Crohn's disease have yielded conflicting results. A …

ACG clinical guideline: management of Crohn's disease in adults

GR Lichtenstein, EV Loftus, KL Isaacs… - Official journal of the …, 2018 - journals.lww.com
Crohn's disease is an idiopathic inflammatory disorder of unknown etiology with genetic,
immunologic, and environmental influences. The incidence of Crohn's disease has steadily …

[HTML][HTML] Infliximab reduces endoscopic, but not clinical, recurrence of Crohn's disease after ileocolonic resection

M Regueiro, BG Feagan, B Zou, J Johanns, MA Blank… - Gastroenterology, 2016 - Elsevier
Background & Aims Most patients with Crohn's disease (CD) eventually require an intestinal
resection. However, CD frequently recurs after resection. We performed a randomized trial to …

Management of Crohn's disease in adults

GR Lichtenstein, SB Hanauer… - Official journal of the …, 2009 - journals.lww.com
Guidelines for clinical practice are intended to suggest preferable approaches to particular
medical problems as established by interpretation and collation of scientifically valid …

Differential regulation of interleukin 17 and interferon γ production in inflammatory bowel disease

L Rovedatti, T Kudo, P Biancheri, M Sarra, CH Knowles… - Gut, 2009 - gut.bmj.com
Background and Aims: Interleukin 17 (IL17) is now known to be involved in a number of
chronic inflammatory disorders. However, the mechanisms regulating its production in …

IOIBD technical review on endoscopic indices for Crohn's disease clinical trials

L Vuitton, P Marteau, WJ Sandborn, BG Levesque… - Gut, 2016 - gut.bmj.com
Background Crohn's disease (CD) is a chronic disabling and progressive IBD. Only
strategies looking beyond symptoms and based on tight monitoring of objective signs of …

A new antimesenteric functional end-to-end handsewn anastomosis: surgical prevention of anastomotic recurrence in Crohn's disease

T Kono, T Ashida, Y Ebisawa, N Chisato… - Diseases of the colon …, 2011 - journals.lww.com
BACKGROUND: Recurrence of Crohn's disease usually occurs at anastomotic sites.
OBJECTIVE: A new anastomosis technique (Kono-S anastomosis) designed to minimize …

Postoperative recurrent luminal Crohn's disease: a systematic review

P De Cruz, MA Kamm, L Prideaux… - Inflammatory bowel …, 2012 - academic.oup.com
Despite improved immunosuppressive therapy, surgical resection is still often required for
uncontrolled inflammatory disease and the stenosing and perforating complications of …

American Gastroenterological Association Institute technical review on the management of Crohn's disease after surgical resection

M Regueiro, F Velayos, JB Greer, C Bougatsos… - …, 2017 - gastrojournal.org
Crohn's disease (CD) is a chronic, disabling gastroin-testinal disease with a rising incidence
and prevalence. 1 Affecting approximately 1 in 300 people in the Western world, CD …