[HTML][HTML] Biocatalysis
Biocatalysis has become an important aspect of modern organic synthesis, both in
academia and across the chemical and pharmaceutical industries. Its success has been …
academia and across the chemical and pharmaceutical industries. Its success has been …
Advances in ultrahigh-throughput screening for directed enzyme evolution
U Markel, KD Essani, V Besirlioglu, J Schiffels… - Chemical Society …, 2020 - pubs.rsc.org
Enzymes are versatile catalysts and their synthetic potential has been recognized for a long
time. In order to exploit their full potential, enzymes often need to be re-engineered or …
time. In order to exploit their full potential, enzymes often need to be re-engineered or …
Transaminases for industrial biocatalysis: novel enzyme discovery
SA Kelly, S Mix, TS Moody, BF Gilmore - Applied microbiology and …, 2020 - Springer
Transaminases (TAms) are important enzymes for the production of chiral amines for the
pharmaceutical and fine chemical industries. Novel TAms for use in these industries have …
pharmaceutical and fine chemical industries. Novel TAms for use in these industries have …
A plurizyme with transaminase and hydrolase activity catalyzes cascade reactions
S Roda, L Fernandez‐Lopez, M Benedens… - Angewandte …, 2022 - Wiley Online Library
Engineering dual‐function single polypeptide catalysts with two abiotic or biotic catalytic
entities (or combinations of both) supporting cascade reactions is becoming an important …
entities (or combinations of both) supporting cascade reactions is becoming an important …
Enzyme adaptation to habitat thermal legacy shapes the thermal plasticity of marine microbiomes
Microbial communities respond to temperature with physiological adaptation and
compositional turnover. Whether thermal selection of enzymes explains marine microbiome …
compositional turnover. Whether thermal selection of enzymes explains marine microbiome …
Synthesis of 12-aminododecenoic acid by coupling transaminase to oxylipin pathway enzymes
A Coenen, M Ferrer, KE Jaeger, U Schörken - Applied Microbiology and …, 2023 - Springer
Biobased polymers derived from plant oils are sustainable alternatives to petro based
polymers. In recent years, multienzyme cascades have been developed for the synthesis of …
polymers. In recent years, multienzyme cascades have been developed for the synthesis of …
Production of l-Theanine by Escherichia coli in the Absence of Supplemental Ethylamine
R Hagihara, S Ohno, M Hayashi… - Applied and …, 2021 - Am Soc Microbiol
ABSTRACT l-Theanine is a nonproteinogenic amino acid present almost exclusively in tea
plants and is beneficial for human health. For industrial production, l-theanine is …
plants and is beneficial for human health. For industrial production, l-theanine is …
Metabolic engineering of Pseudomonas putida for production of vanillylamine from lignin‐derived substrates
JHC Manfrão‐Netto, F Lund… - Microbial …, 2021 - Wiley Online Library
Whole‐cell bioconversion of technical lignins using Pseudomonas putida strains
overexpressing amine transaminases (ATAs) has the potential to become an eco‐efficient …
overexpressing amine transaminases (ATAs) has the potential to become an eco‐efficient …
Genome mining and characterisation of a novel transaminase with remote stereoselectivity
DP Gavin, FJ Reen, J Rocha-Martin, I Abreu-Castilla… - Scientific reports, 2019 - nature.com
Microbial enzymes from pristine niches can potentially deliver disruptive opportunities in
synthetic routes to Active Pharmaceutical Ingredients and intermediates in the …
synthetic routes to Active Pharmaceutical Ingredients and intermediates in the …
ω-Transaminase-Mediated Asymmetric Synthesis of (S)-1-(4-Trifluoromethylphenyl)Ethylamine
CJC Rodrigues, M Ferrer, CCCR de Carvalho - Catalysts, 2021 - mdpi.com
The pivotal role played by ω-transaminases (ω-TAs) in the synthesis of chiral amines used
as building blocks for drugs and pharmaceuticals is widely recognized. However, chiral …
as building blocks for drugs and pharmaceuticals is widely recognized. However, chiral …