[HTML][HTML] Nonalcoholic fatty liver disease: a precursor of the metabolic syndrome

A Lonardo, S Ballestri, G Marchesini, P Angulo… - Digestive and Liver …, 2015 - Elsevier
The conventional paradigm of nonalcoholic fatty liver disease representing the “hepatic
manifestation of the metabolic syndrome” is outdated. We identified and summarized …

Polycystic ovary syndrome: an evolutionary adaptation to lifestyle and the environment

J Parker, C O'brien, J Hawrelak, FL Gersh - International journal of …, 2022 - mdpi.com
Polycystic ovary syndrome (PCOS) is increasingly recognized as a complex metabolic
disorder that manifests in genetically susceptible women following a range of negative …

Obesity and bone health: a complex link

J Hou, C He, W He, M Yang, X Luo, C Li - Frontiers in cell and …, 2020 - frontiersin.org
So far, the connections between obesity and skeleton have been extensively explored, but
the results are inconsistent. Obesity is thought to affect bone health through a variety of …

Triglycerides and glucose index: a useful indicator of insulin resistance

G Unger, SF Benozzi, F Perruzza… - … y Nutrición (English …, 2014 - Elsevier
Introduction Insulin resistance assessment requires sophisticated methodology of difficult
application. Therefore, different estimators for this condition have been suggested. The aim …

Central nervous system regulation of eating: Insights from human brain imaging

OM Farr, RL Chiang-shan, CS Mantzoros - Metabolism, 2016 - Elsevier
Appetite and body weight regulation are controlled by the central nervous system (CNS) in a
rather complicated manner. The human brain plays a central role in integrating internal and …

Epigenetics and epigenomics: implications for diabetes and obesity

ED Rosen, KH Kaestner, R Natarajan, ME Patti… - Diabetes, 2018 - Am Diabetes Assoc
The American Diabetes Association convened a research symposium,“Epigenetics and
Epigenomics: Implications for Diabetes and Obesity” on 17–19 November 2017 …

Insulin‐like growth factor 1 has multisystem effects on foetal and preterm infant development

A Hellström, D Ley, I Hansen‐Pupp, B Hallberg… - Acta …, 2016 - Wiley Online Library
Poor postnatal growth after preterm birth does not match the normal rapid growth in utero
and is associated with preterm morbidities. Insulin‐like growth factor 1 (IGF‐1) axis is the …

Link between insulin resistance and hypertension: What is the evidence from evolutionary biology?

MS Zhou, A Wang, H Yu - Diabetology & metabolic syndrome, 2014 - Springer
Insulin resistance and hypertension are considered as prototypical “diseases of civilization”
that are manifested in the modern environment as plentiful food and sedentary life. The …

Pharmacological concentrations of irisin increase cell proliferation without influencing markers of neurite outgrowth and synaptogenesis in mouse H19-7 hippocampal …

HS Moon, F Dincer, CS Mantzoros - Metabolism, 2013 - Elsevier
Abstract Aims/Hypothesis Irisin is a novel, myocyte secreted, hormone that has been
proposed to mediate the beneficial effects of exercise on metabolism. Irisin is expressed, at …

Glucose as a major antioxidant: when, what for and why it fails?

A Cherkas, S Holota, T Mdzinarashvili, R Gabbianelli… - Antioxidants, 2020 - mdpi.com
A human organism depends on stable glucose blood levels in order to maintain its
metabolic needs. Glucose is considered to be the most important energy source, and …