Pentraxin 3 in cardiovascular disease

G Ristagno, F Fumagalli, B Bottazzi… - Frontiers in …, 2019 - frontiersin.org
The long pentraxin PTX3 is a member of the pentraxin family produced locally by stromal
and myeloid cells in response to proinflammatory signals and microbial moieties. The …

Inflammation in end‐stage renal disease—what have we learned in 10 years?

JJ Carrero, P Stenvinkel - Seminars in dialysis, 2010 - Wiley Online Library
The first reports connecting uremic inflammation with a wasted and atherogenic phenotype
and poor outcome initiated in the late 1990s. Since then, about 3500 publications appear on …

Masked hypertension and elevated nighttime blood pressure in CKD: prevalence and association with target organ damage

PE Drawz, AB Alper, AH Anderson… - Clinical Journal of the …, 2016 - journals.lww.com
Results The percentages of participants with controlled BP, white-coat, masked, and
sustained hypertension were 49.3%, 4.1%, 27.8%, and 18.8%, respectively. Compared with …

[HTML][HTML] Plasma endocan levels associate with inflammation, vascular abnormalities, cardiovascular events, and survival in chronic kidney disease

MI Yilmaz, D Siriopol, M Saglam, YG Kurt, HU Unal… - Kidney international, 2014 - Elsevier
Plasma endocan levels are elevated in a large number of diseases, and may reflect
endothelial cell dysfunction. There are currently no data on endocan in patients with chronic …

The long pentraxin PTX3: a modulator of the immunoinflammatory response in atherosclerosis and cardiovascular diseases

GD Norata, C Garlanda, AL Catapano - Trends in cardiovascular medicine, 2010 - Elsevier
Innate and adaptive immune responses participate in atherosclerosis. Pentraxins, an
essential component of the humoral arm of innate immunity, are a superfamily of acute …

Pentraxins in the activation and regulation of innate immunity

K Daigo, A Inforzato, I Barajon, C Garlanda… - Immunological …, 2016 - Wiley Online Library
Humoral fluid phase pattern recognition molecules (PRM s) are a key component of the
activation and regulation of innate immunity. Humoral PRM s are diverse. We focused on the …

Determination of physiological plasma pentraxin 3 (PTX3) levels in healthy populations

K Yamasaki, M Kurimura, T Kasai, M Sagara… - Clinical chemistry and …, 2009 - degruyter.com
Background: The aim of this study was to evaluate the distribution of pentraxin 3 (PTX3)
values in healthy subjects and to characterize its relationship with gender, age, body mass …

Chemotherapy-induced upregulation of small extracellular vesicle-associated PTX3 accelerates breast cancer metastasis

CA Wills, X Liu, L Chen, Y Zhao, CM Dower… - Cancer research, 2021 - AACR
Although neoadjuvant chemotherapy is a standard component of breast cancer treatment,
recent evidence suggests that chemotherapeutic drugs can promote metastasis through …

Pentraxin 3 induces vascular endothelial dysfunction through a P-selectin/matrix metalloproteinase-1 pathway

A Carrizzo, P Lenzi, C Procaccini, A Damato… - Circulation, 2015 - Am Heart Assoc
Background—Pentraxin 3 (PTX3), the prototype of long pentraxins, has been described to
be associated with endothelial dysfunction in different cardiovascular disorders. No study …

Update on the role of Pentraxin 3 in atherosclerosis and cardiovascular diseases

M Casula, F Montecucco, A Bonaventura… - Vascular …, 2017 - Elsevier
Abstract Pentraxin 3 (PTX3) is an acute-phase protein that was recently demonstrated to
play pleiotropic activities in cardiovascular (CV) diseases. Tumor necrosis factor and …