The glial cell of the peripheral nervous system (PNS), the Schwann cell (SC), counts among
the most multifaceted cells of the body. During development, SCs secure neuronal survival …

Glial cells in the peripheral nervous system (PNS), which arise from the neural crest, include
axon-associated Schwann cells (SCs) in nerves, synapse-associated SCs at the …

Neural crest cells are highly multipotent stem cells, but it remains unclear how their fate
restriction to specific fates occurs. The direct fate restriction model hypothesises that …

Aplasia cutis congenita (ACC) is a congenital epidermal defect of the midline scalp and has
been proposed to be due to a primary keratinocyte abnormality. Why it forms mainly at this …

Melanocytes, which originate from the neuroectoderm, are specialized cells responsible for
producing pigments and possessing a dendritic morphology. These cells migrate to the …

Transition of cytosine to thymine in CpG dinucleotides is the most frequent type of mutation
in cancer. This increased mutability is commonly attributed to the spontaneous deamination …

Despite their indisputable importance in neuroblastoma (NB) pathology, knowledge of the
bases of NB plasticity and heterogeneity remains incomplete. They may be rooted in …

Neuroblastoma is a childhood developmental cancer; however, its embryonic origins remain
poorly understood. Moreover, in-depth studies of early tumor-driving events are limited …

Schwann cells are glial cells of the peripheral nervous system. They exist in several
subtypes and perform a variety of functions in nerves. Their derivation and culture in vitro are …

Recent years have improved our understanding of the plasticity of cell types behind
inducing, building, and maintaining different types of teeth. The latest efforts were aided by …