H-NS: a universal regulator for a dynamic genome
CJ Dorman - Nature Reviews Microbiology, 2004 - nature.com
The effect of the bacterial heat-stable nucleoid-structuring (H-NS) protein on gene
expression is overwhelmingly negative and extends throughout the genome, pointing to an …
expression is overwhelmingly negative and extends throughout the genome, pointing to an …
The role of nucleoid‐associated proteins in the organization and compaction of bacterial chromatin
RT Dame - Molecular microbiology, 2005 - Wiley Online Library
The bacterial chromosomal DNA is folded into a compact structure called nucleoid. The
shape and size of this 'body'is determined by a number of factors. Major players are DNA …
shape and size of this 'body'is determined by a number of factors. Major players are DNA …
Extremotolerant tardigrade genome and improved radiotolerance of human cultured cells by tardigrade-unique protein
T Hashimoto, DD Horikawa, Y Saito… - Nature …, 2016 - nature.com
Tardigrades, also known as water bears, are small aquatic animals. Some tardigrade
species tolerate almost complete dehydration and exhibit extraordinary tolerance to various …
species tolerate almost complete dehydration and exhibit extraordinary tolerance to various …
The antimicrobial polymer PHMB enters cells and selectively condenses bacterial chromosomes
K Chindera, M Mahato, A Kumar Sharma, H Horsley… - Scientific reports, 2016 - nature.com
To combat infection and antimicrobial resistance, it is helpful to elucidate drug mechanism
(s) of action. Here we examined how the widely used antimicrobial polyhexamethylene …
(s) of action. Here we examined how the widely used antimicrobial polyhexamethylene …
Characterization of broadly pleiotropic phenotypes caused by an hfq insertion mutation in Escherichia coli K‐12
HCT Tsui, HCE Leung, ME Winkler - Molecular microbiology, 1994 - Wiley Online Library
The region immediately downstream from the miaA tRNA modification gene at 94.8 min
contains the hfq gene and the hflA region, which are important in the bacteriophage Qβ and …
contains the hfq gene and the hflA region, which are important in the bacteriophage Qβ and …
H‐NS: a modulator of environmentally regulated gene expression
H‐NS is a small chromatin‐associated protein found in enterobacteria. H‐NS has affinity for
all types of nucleic acids but binds preferentially to intrinsically curved DNA. The major role …
all types of nucleic acids but binds preferentially to intrinsically curved DNA. The major role …
Silencing of xenogeneic DNA by H-NS—facilitation of lateral gene transfer in bacteria by a defense system that recognizes foreign DNA
WW Navarre, M McClelland, SJ Libby… - Genes & …, 2007 - genesdev.cshlp.org
Lateral gene transfer has played a prominent role in bacterial evolution, but the mechanisms
allowing bacteria to tolerate the acquisition of foreign DNA have been incompletely defined …
allowing bacteria to tolerate the acquisition of foreign DNA have been incompletely defined …
H-NS mediated compaction of DNA visualised by atomic force microscopy
RT Dame, C Wyman, N Goosen - Nucleic acids research, 2000 - academic.oup.com
Abstract The Escherichia coli H-NS protein is a nucleoid-associated protein involved in gene
regulation and DNA compaction. To get more insight into the mechanism of DNA …
regulation and DNA compaction. To get more insight into the mechanism of DNA …
A divalent switch drives H-NS/DNA-binding conformations between stiffening and bridging modes
Heat-stable nucleoid structuring protein (H-NS) is an abundant prokaryotic protein that plays
important roles in organizing chromosomal DNA and gene silencing. Two controversial …
important roles in organizing chromosomal DNA and gene silencing. Two controversial …
Gene order and chromosome dynamics coordinate spatiotemporal gene expression during the bacterial growth cycle
P Sobetzko, A Travers… - Proceedings of the …, 2012 - National Acad Sciences
In Escherichia coli crosstalk between DNA supercoiling, nucleoid-associated proteins and
major RNA polymerase σ initiation factors regulates growth phase-dependent gene …
major RNA polymerase σ initiation factors regulates growth phase-dependent gene …