Studying human respiratory disease in animals–role of induced and naturally occurring models

K Williams, J Roman - The Journal of pathology, 2016 - Wiley Online Library
Respiratory disorders like asthma, emphysema, and pulmonary fibrosis affect millions of
Americans and many more worldwide. Despite advancements in medical research that have …

Idiopathic pulmonary fibrosis in West Highland white terriers: An update

C Clercx, A Fastrès, E Roels - The Veterinary Journal, 2018 - Elsevier
Canine idiopathic pulmonary fibrosis (CIPF) affects middle-aged to older dogs of a single
breed, mainly the West Highland white terrier (WHWT), which is suggestive of a genetic …

A system biology study of BALF from patients affected by idiopathic pulmonary fibrosis (IPF) and healthy controls

C Landi, E Bargagli, A Carleo, L Bianchi… - PROTEOMICS …, 2014 - Wiley Online Library
Background Idiopathic pulmonary fibrosis (IPF) is a devastating interstitial lung disease
characterized by progressive loss of the alveolar integrity, recruitment, and activation of …

Decorin alleviated chronic hydrocephalus via inhibiting TGF-β1/Smad/CTGF pathway after subarachnoid hemorrhage in rats

H Yan, Y Chen, L Li, J Jiang, G Wu, Y Zuo, JH Zhang… - Brain research, 2016 - Elsevier
Chronic hydrocephalus is one of the severe complications after subarachnoid hemorrhage
(SAH). However, there is no efficient treatment for the prevention of chronic hydrocephalus …

Biomarkers of infectious pneumonia in naturally infected calves

M Ider, M Maden - American Journal of Veterinary Research, 2022 - Am Vet Med Assoc
OBJECTIVE To investigate the clinical value of selected biomarkers for evaluation of
systemic inflammatory response and pulmonary inflammation and damage pattern in calves …

Further characterization of computed tomographic and clinical features for staging and prognosis of idiopathic pulmonary fibrosis in West Highland white terriers

F Thierry, I Handel, G Hammond… - Veterinary radiology …, 2017 - Wiley Online Library
Idiopathic pulmonary fibrosis is an interstitial lung disease of unknown etiology resulting in
progressive interstitial fibrosis, with a known predilection in West Highland white terriers. In …

Transforming growth factor beta 1 activation, storage, and signaling pathways in idiopathic pulmonary fibrosis in dogs

E Krafft, P Lybaert, E Roels, HP Laurila… - Journal of veterinary …, 2014 - Wiley Online Library
Background The pathogenesis of idiopathic pulmonary fibrosis (IPF) in dogs is poorly
understood. In human, transforming growth factor β1 (TGF‐β1) is considered central in the …

The LRG-TGF-β-Alk-1/TGFßRII-Smads as predictive biomarkers of chronic hydrocephalus after aneurysmal subarachnoid hemorrhage

D Ma, L Ma, Y Zhao, Y Li, W Ye… - Journal of Neurological …, 2023 - thieme-connect.com
Background Chronic hydrocephalus is a common complication of aneurysmal subarachnoid
hemorrhage (aSAH); however, the risk factors and the mechanisms underlying its …

Matrix metalloproteinase‐2,‐7, and‐9 activities in dogs with idiopathic pulmonary fibrosis compared to healthy dogs and dogs with other respiratory diseases

M Määttä, HP Laurila, S Holopainen… - Journal of Veterinary …, 2021 - Wiley Online Library
Background Canine idiopathic pulmonary fibrosis (CIPF) is a chronic, interstitial lung
disease that mainly affects West Highland white terriers (WHWTs) and is characterized by …

Nanoparticles combined with growth factors: recent progress and applications

C Chu, J Deng, L Liu, Y Cao, X Wei, J Li, Y Man - Rsc Advances, 2016 - pubs.rsc.org
Increasing attention has been focused on the applications of nanoparticles combined with
growth factors (NPs/GFs) due to the substantial functions of GFs in regenerative medicine …