Inhibition of hypothalamic FTO activates STAT3 signal through ERK1/2 associated with reductions in food intake and body weight
F Hu, HJ Yan, CX Gao, WW Sun, YS Long - Neuroendocrinology, 2023 - karger.com
Introduction: Fat mass and obesity-associated (FTO) gene is strongly associated with obesity
which brings a major health threat. Altered expression of its encoded protein FTO in the …
which brings a major health threat. Altered expression of its encoded protein FTO in the …
[HTML][HTML] Hypothalamic FTO promotes high-fat diet-induced leptin resistance in mice through increasing CX3CL1 expression
S Liu, S Song, S Wang, T Cai, L Qin, X Wang… - The Journal of …, 2024 - Elsevier
Long-term consumption of a high-fat diet (HFD) disrupts energy homeostasis and leads to
weight gain. The fat mass and obesity-associated (FTO) gene has been consistently …
weight gain. The fat mass and obesity-associated (FTO) gene has been consistently …
BAC transgenic zebrafish reveal hypothalamic enhancer activity around obesity associated SNP rs9939609 within the human FTO gene
S Rinkwitz, FS Geng, E Manning, M Suster… - genesis, 2015 - Wiley Online Library
Summary Single Nucleotide Polymorphisms in FTO intron 1 have been associated with
obesity risk, leading to the hypothesis that FTO is the obesity‐related gene. However, other …
obesity risk, leading to the hypothesis that FTO is the obesity‐related gene. However, other …