[HTML][HTML] Inflammation-mediated tissue damage in pulmonary tuberculosis and host-directed therapeutic strategies

D Tiwari, AR Martineau - Seminars in Immunology, 2023 - Elsevier
Abstract Treatment of tuberculosis (TB) involves the administration of anti-mycobacterial
drugs for several months. The emergence of drug-resistant strains of Mycobacterium …

Updates in pulmonary drug‐resistant tuberculosis pharmacotherapy: A focus on BPaL and BPaLM

DJ Holger, A Althubyani, T Morrisette… - … : The Journal of …, 2024 - Wiley Online Library
Drug‐resistant tuberculosis (TB) is a major public health concern and contributes to high
morbidity and mortality. New evidence supports the use of shorter duration, all‐oral …

Tuberculosis: the past, the present and the future

CFN Koegelenberg, OD Schoch, C Lange - Respiration, 2021 - karger.com
The current coronavirus disease 2019 (COVID-19) pandemic caused by the severe acute
respiratory syndrome coronavirus-2 (SARS-CoV-2) has not only highlighted the vulnerability …

Concordance of three approaches for operationalizing outcome definitions for multidrug-resistant TB

C Zeng, CD Mitnick, C Hewison… - … of Tuberculosis and …, 2023 - ingentaconnect.com
BACKGROUND: The WHO provides standardized outcome definitions for rifampicin-
resistant (RR) and multidrug-resistant (MDR) TB. However, operationalizing these …

Early microbiologic markers of pulmonary tuberculosis treatment outcomes

MS Paradkar, NN Pradhan, S Balaji… - Annals of the …, 2023 - atsjournals.org
Rationale: Earlier biomarkers of pulmonary tuberculosis (PTB) treatment outcomes are
critical to monitor shortened anti-TB treatment (ATT). Objectives: To identify early …

[HTML][HTML] Treatment adherence and clinical outcomes amongst in people with drug-susceptible tuberculosis using medication monitor and differentiated care approach …

S Charalambous, N Maraba, L Jennings… - …, 2024 - thelancet.com
Background Poor treatment adherence contributes to lower treatment completion and higher
loss to follow-up among people with tuberculosis (PWTB). Medication monitors have shown …

Adjunctive administration of parabiotic Lactobacillus sakei CVL-001 ameliorates drug-induced toxicity and pulmonary inflammation during antibiotic treatment for …

H Kim, EJ Song, E Choi, KW Kwon, JH Park… - International …, 2024 - Elsevier
Tuberculosis (TB) treatment requires a long therapeutic duration and induces adverse
effects such as hepatotoxicity, causing discontinuation of treatment. Reduced adherence to …

Characterization of the infant immune system and the influence and immunogenicity of BCG vaccination in infant and adult rhesus macaques

C Sarfas, AD White, L Sibley, AL Morrison… - Frontiers in …, 2021 - frontiersin.org
In many countries where tuberculosis (TB) is endemic, the Bacillus Calmette–Guérin (BCG)
vaccine is given as close to birth as possible to protect infants and children from severe …

Updated WHO definitions for tuberculosis outcomes: Simplified, unified and future-proofed

JAM Stadler - African Journal of Thoracic and Critical Care Medicine, 2022 - journals.co.za
Standardised outcome definitions are crucial for monitoring and comparing effectiveness of
treatment strategies for tuberculosis (TB) over time and across geographies. The World …

Identification of hub genes and establishment of a diagnostic model in tuberculosis infection

C Liu, X Li - AMB Express, 2024 - Springer
Tuberculosis (TB) poses significant challenges due to its high transmissibility within
populations and intrinsic resistance to treatment, rendering it a formidable respiratory …