Helium ion beam therapy for the treatment of cancer was one of several developed and
studied particle treatments in the 1950s, leading to clinical trials beginning in 1975 at the …

While proton radiation therapy offers substantially better dose distribution characteristics
than photon radiation therapy in certain clinical applications, data demonstrating a …

We asked whether pharmacological stimulation of endogenous neural precursor cells
(NPCs) may promote cognitive recovery and brain repair, focusing on the drug metformin, in …

Pediatric brain tumors (PBTs), the most common solid tumors of childhood, are a leading
cause of cancerrelated morbidity. Advancements in treatment have significantly improved …

Advances in multimodality therapy have led to childhood cancer cure rates over 80%.
However, surgery, chemotherapy, and radiotherapy may lead to debilitating or even fatal …

Proton therapy is increasingly being used as a radiation therapy modality. There is
uncertainty about the biological effectiveness of protons relative to photon therapies as it …

The pace of technological innovation over the past three decades has transformed the field
of radiotherapy into one of the most technologically intense disciplines in medicine …

Simple Summary Medulloblastoma is the most common pediatric brain tumor, comprising
one-third of all pediatric brain tumors, and originating in the posterior fossa of the brain. The …

Critical discoveries over the past two decades have transformed our understanding of
medulloblastoma from a single entity into a clinically and biologically heterogeneous …

Cancer is a leading cause of death in children with tumors of the central nervous system, the
most commonly encountered solid malignancies in this population. Radiotherapy (RT) is an …