In this study, a series of thiosemicarbazide derivatives 12–14, 1, 2, 4-triazol-3-thione
derivatives 15–17 and compounds bearing 2-(4H-1, 2, 4-triazole-3-ylthio) acetamide …

Abstract Hepatitis C virus (HCV) NS5B polymerase is an important and attractive target for
the development of anti-HCV drugs. Here we report on the design, synthesis and evaluation …

A variety of novel thiazolidin‐4‐one himachalene derivatives were designed and
synthesized through hetero‐cyclization of thiosemicarbazone analogs that have previously …

Prodrugs are the pharmacologically inactive derivatives of active drugs typically intended to
optimize the exposure of active drug at target site, through manipulation of its …

Mycobacteria regulate the synthesis of mycolic acid through the fatty acid synthase system
type 1 (FAS I) and the fatty acid synthase system type-2 (FAS-II). Because mammalian cells …

Thiazolidinone and its derivatives are very promising scaffolds for various biological
activities like antimicrobial, antitubercular, anticancer, anti-HIV, anti-inflammatory …

Novel 2-aryl-5-non-substituted/methyl-1, 3-thiazolidine-4-one derivatives 14-33 carrying L-
valine core were synthesized by the reaction of acylhydrazones 4-13 with thioglycolic …

Herein, we reported on a new series of hydrazono bis-4-oxothiazolidines during the reaction
of (hydrazinecarbonothioyl) hydrazinecarbothioamides with dimethyl acetylenedicarboxylate …

Since many decades, causes of death due to health issues have tremendously increased
and still increasing. Deaths due to non-communicable diseases increase in India. According …

Amaç: Bu tez kapsamında tüberküloz (TB) hastalığına yol açan Mycobacterium tuberculosis'
in yağ asit sentaz II (FAS-II) yolağı üzerinde bulunan enoil-açil taşıyıcı protein redüktaz …