Revolving ATPase motors as asymmetrical hexamers in translocating lengthy dsDNA via conformational changes and electrostatic interactions in phi29, T7 …

T Weitao, G Grandinetti, P Guo - Exploration, 2023 - Wiley Online Library
Investigations of the parallel architectures of biomotors in both prokaryotic and eukaryotic
systems suggest a similar revolving mechanism in the use of ATP to drive translocation of …

Physical Virology: From the State-of-the-Art Research to the Future of Applied Virology

M Comas-Garcia, S Rosales-Mendoza - 2023 - books.google.com
This book highlights key findings generated during the past years from the main disciplines
that constitute Physical Virology, from theoretical physics and simulations to material …

In vitro Analysis of O-Antigen-Specific Bacteriophage P22 Inactivation by Salmonella Outer Membrane Vesicles

MS Stephan, NK Broeker, A Saragliadis… - Frontiers in …, 2020 - frontiersin.org
Bacteriophages use a large number of different bacterial cell envelope structures as
receptors for surface attachment. As a consequence, bacterial surfaces represent a major …

Role of DNA–DNA sliding friction and nonequilibrium dynamics in viral genome ejection and packaging

M Fizari, N Keller, PJ Jardine… - Nucleic acids research, 2023 - academic.oup.com
Many viruses eject their DNA via a nanochannel in the viral shell, driven by internal forces
arising from the high-density genome packing. The speed of DNA exit is controlled by friction …

Spontaneous domain formation in spherically confined elastic filaments

T Curk, JD Farrell, J Dobnikar, R Podgornik - Physical review letters, 2019 - APS
Although the free energy of a genome packing into a virus is dominated by DNA-DNA
interactions, ordering of the DNA inside the capsid is elasticity driven, suggesting general …

Evidence that a catalytic glutamate and an 'Arginine Toggle'act in concert to mediate ATP hydrolysis and mechanochemical coupling in a viral DNA packaging motor

D Ortiz, D delToro, M Ordyan, J Pajak… - Nucleic acids …, 2019 - academic.oup.com
ASCE ATPases include ring-translocases such as cellular helicases and viral DNA
packaging motors (terminases). These motors have conserved Walker A and B motifs that …

Virus Mechanics: A Structure-Based Biological Perspective

MG Mateu - Physical Virology: From the State-of-the-Art Research …, 2023 - Springer
A virus particle possesses a certain degree of stiffness, brittleness, strength against
disruption by mechanical force, and resistance to material fatigue. Atomic force microscopy …

Function of a viral genome packaging motor from bacteriophage T4 is insensitive to DNA sequence

Y Mo, N Keller, D delToro… - Nucleic acids …, 2020 - academic.oup.com
Many viruses employ ATP-powered motors during assembly to translocate DNA into
procapsid shells. Previous reports raise the question if motor function is modulated by …

Structure and the role of filling rate on model dsDNA packed in a phage capsid

C Bores, BM Pettitt - Physical Review E, 2020 - APS
The conformation of DNA inside bacteriophages is of paramount importance for
understanding packaging and ejection mechanisms. Models describing the structure of the …

Mechanical properties of viruses

PJ de Pablo, MG Mateu - Structure and Physics of Viruses: An Integrated …, 2024 - Springer
Structural biology techniques have greatly contributed to unveiling the interplay between
molecular structure, physico-chemical properties, and biological function of viruses. In recent …