Proliferative vitreoretinopathy: an update on the current and emerging treatment options

L Ferro Desideri, D Artemiev, S Zandi… - Graefe's Archive for …, 2024 - Springer
Proliferative vitreoretinopathy (PVR) remains the main cause of failure in retinal detachment
(RD) surgery and a demanding challenge for vitreoretinal surgeons. Despite the large …

Vitreoschisis‐induced vitreous cortex remnants in proliferative vitreoretinopathy: A comprehensive review from basic research to clinical practice

KA van Overdam, M Veckeneer, E Kiliç… - Acta …, 2024 - Wiley Online Library
Proliferative vitreoretinopathy (PVR) significantly impacts the prognosis of rhegmatogenous
retinal detachment (RRD), one of the most critical and increasing causes of vision loss in the …

Early use of intravitreal triamcinolone to inhibit traumatic proliferative vitreoretinopathy: a randomised clinical trial

H Guo, J Yu, T He, S Chen, Z Sun, J Zhang… - British Journal of …, 2024 - bjo.bmj.com
Aims To evaluate the efficacy and safety of intravitreal triamcinolone acetonide (TA) injection
at the end of emergency surgery for open globe injury (OGI) to suppress traumatic …

[HTML][HTML] Proliferative Vitreoretinopathy in Retinal Detachment: Perspectives on Building a Digital Twin Model Using Nintedanib

G Visioli, A Romaniello, L Spinoglio… - International Journal of …, 2024 - mdpi.com
Proliferative vitreoretinopathy (PVR) is a pathological process characterized by the formation
of fibrotic membranes that contract and lead to recurrent retinal detachment. Pars plana …

Clinical therapeutics for proliferative vitreoretinopathy in retinal detachment

F Sabatino, P Banerjee, MMK Muqit - Survey of Ophthalmology, 2024 - Elsevier
Proliferative vitreoretinopathy (PVR) is an abnormal and prolonged healing response to
retinal injury (retinal detachment, post-retinal detachment surgery) characterised by …

Applications of human amniotic membrane patching assisted vitrectomy in the management of postoperative PVR in complex retinal detachments

T Caporossi, A Molle, MM Carlà, SM Picardi… - Journal of Clinical …, 2023 - mdpi.com
Human amniotic membranes (hAMs) are extraembryonic tissues currently employed in the
treatment of many ocular and systemic diseases. Several reports indicate that hAMs can …

Efficacy of 5-fluorouracil (5-FU) and low molecular weight heparin (LMWH) in high-risk pediatric retinal detachment; randomized clinical trial

M Nasr, A Abdelhadi, A Bessa, TM Ibrahim - BMC ophthalmology, 2024 - Springer
Background Pediatric rhegmatogenous retinal detachments (PRRDs) are complex, rare
occurrences and are often related to trauma or congenital abnormalities. Children often do …

INTRAVITREAL METHOTREXATE INJECTION FOR THE TREATMENT AND PREVENTION OF PROLIFERATIVE VITREORETINOPATHY

PJ Hughes, N Bhagat, OG Gonzalez-Martinez… - Retina, 2024 - journals.lww.com
Purpose: To report on our experience using intravitreal methotrexate (MTX) in patients with
retinal detachment associated with proliferative vitreoretinopathy and/or open globe injury …

Proliferative Vitreoretinopathy: Pathophysiology and Therapeutic Approaches

JB Lin, F Wu, LA Kim - International Ophthalmology Clinics, 2024 - journals.lww.com
LAK was supported by the National Eye Institute via Grant No. R01EY027739 and the
Department of Defense via Grant No. W81XWH1910824. JBL was supported by the …

Exosomes-based dual drug-loaded nanocarrier for targeted and multiple proliferative vitreoretinopathy therapy

P Zhao, J Wang, H Huang, Z Chen… - Regenerative …, 2024 - academic.oup.com
Proliferative vitreoretinopathy (PVR) is a common cause of vision loss after retinal
reattachment surgery and ocular trauma. The key pathogenic mechanisms of PVR …