The pathogenesis of idiopathic pulmonary fibrosis (IPF) involves a complex interplay of cell
types and signaling pathways. Recurrent alveolar epithelial cell (AEC) injury may occur in …

Oxidative stress has been associated with a number of human fibrotic diseases, including
idiopathic pulmonary fibrosis (IPF). Although oxidative stress is associated with both fibrosis …

Idiopathic Pulmonary Fibrosis (IPF) is a chronic lung disease characterized by scar
formation and respiratory insufficiency, which progressively leads to death. Pulmonary …

Pulmonary fibrosis is characterized by pronounced collagen deposition and myofibroblast
expansion, whose origin and plasticity remain elusive. We utilized a fate-mapping approach …

Background and Purpose Group III pulmonary hypertension (PH) is a highly lethal and
widespread lung disorder that is a common complication in idiopathic pulmonary fibrosis …

Clinical lung transplantation has rapidly established itself as the gold standard of treatment
for end‐stage lung diseases in a restricted group of patients since the first successful lung …

Bronchiolitis obliterans syndrome (BOS) is considered an airway-centered disease, with
bronchiolitis obliterans (BO) as pathologic hallmark. However, the histologic spectrum of …

Pulmonary hypertension (PH) is present in an important proportion of patients with interstitial
lung diseases (ILDs), encompassing a large, heterogeneous group of diffuse parenchymal …

Though idiopathic pulmonary fibrosis (IPF) is characterized by single-organ involvement,
many comorbid conditions occur within other organ systems. Patients with IPF may present …

Idiopathic pulmonary fibrosis (IPF) is a fatal lung disease where the additional presence of
pulmonary hypertension (PH) reduces survival. In particular, the presence of coexistent …