Global Cancer Statistics 2022: the trends projection analysis
BS Chhikara, K Parang - Chemical Biology Letters, 2023 - pubs.thesciencein.org
Cancer is one of the most fatal diseases of recent times that causes several deaths every
year. The disease variations in different parts of the world, the impact of available medical …
year. The disease variations in different parts of the world, the impact of available medical …
Beyond chloroquine: Cationic amphiphilic drugs as endosomal escape enhancers for nucleic acid therapeutics
A Debisschop, B Bogaert, C Muntean… - Current Opinion in …, 2024 - Elsevier
Nucleic acid (NA) therapeutics have the potential to treat or prevent a myriad of diseases but
generally require cytosolic delivery to be functional. NA drugs are therefore often …
generally require cytosolic delivery to be functional. NA drugs are therefore often …
Peptide nanostructures-based delivery of DNA nanomaterial therapeutics for regulating gene expression
B Baral, B Panigrahi, A Kar, KD Tulsiyan… - … Therapy-Nucleic Acids, 2023 - cell.com
Self-assembled branched DNA (bDNA) nanomaterials have exhibited their functionality in
various biomedical and diagnostic applications. However, the anionic cellular membrane …
various biomedical and diagnostic applications. However, the anionic cellular membrane …
Cyclic and linear peptides containing alternate WW and RR residues as molecular cargo delivery tools
Cell-impermeable and negatively charged compounds' cellular uptake across the cell
membranes remains challenging. Herein, the synthesis of four linear [(WWRR) 2,(WWRR) …
membranes remains challenging. Herein, the synthesis of four linear [(WWRR) 2,(WWRR) …
Amphiphilic cell-penetrating peptides containing arginine and hydrophobic residues as protein delivery agents
The entry of proteins through the cell membrane is challenging, thus limiting their use as
potential therapeutics. Seven cell-penetrating peptides, designed in our laboratory, were …
potential therapeutics. Seven cell-penetrating peptides, designed in our laboratory, were …
Novel Angiotensin-Converting Enzyme-Inhibitory Peptides Obtained from Trichiurus lepturus: Preparation, Identification and Potential Antihypertensive Mechanism
J Cao, B Xiang, B Dou, J Hu, L Zhang, X Kang, M Lyu… - Biomolecules, 2024 - mdpi.com
Peptides possessing antihypertensive attributes via inhibiting the angiotensin-converting
enzyme (ACE) were derived through the enzymatic degradation of Trichiurus lepturus …
enzyme (ACE) were derived through the enzymatic degradation of Trichiurus lepturus …
Nanotherapeutics and HIV: Four decades of infection canvass the quest for drug development using nanomedical technologies
We have seen four decades of human struggle to cure or eradicate HIV infection since the
first clinical detection of HIV infection. Various developed drugs such as nucleoside reverse …
first clinical detection of HIV infection. Various developed drugs such as nucleoside reverse …
Hydrophobicity: The door to drug delivery
A Falanga, R Bellavita, S Braccia… - Journal of Peptide …, 2024 - Wiley Online Library
The engineering of intracellular delivery systems with the goal of achieving personalized
medicine has been encouraged by advances in nanomaterial science as well as a greater …
medicine has been encouraged by advances in nanomaterial science as well as a greater …
Synthesis and biological evaluation of Bicyclic Peptides containing Arginine and Tryptophan residues
S Darwish, S Mozaffari, E Mohammed… - Chemical Biology …, 2024 - pubs.thesciencein.org
Two bicyclic peptides,[W (WR) 4K]-GFLG-[W (WR) 8E] and [W (WR) 4K]-[W (WR) 4E],
composed of alternate tryptophan (W) and arginine (R) residues in each monocyclic peptide …
composed of alternate tryptophan (W) and arginine (R) residues in each monocyclic peptide …
非天然氨基酸的应用及生物合成策略.
李海宁， 张红兵， 耿革霞， 李冉… - Biotechnology …, 2023 - search.ebscohost.com
非天然氨基酸是一类不受遗传密码子约束的特殊氨基酸, 它们具有独特的空间构型和化学性质,
为多个领域提供了新的资源和机会. 当前, 非天然氨基酸可以通过化学合成和生物合成两种方式 …
为多个领域提供了新的资源和机会. 当前, 非天然氨基酸可以通过化学合成和生物合成两种方式 …