The incidence of invasive fungal infections is increasing worldwide, resulting in more than
1.6 million deaths every year. Due to growing antifungal drug resistance and the limited …

Introduction: Parasitic diseases that pose a threat to human life include leishmaniasis–
caused by protozoan parasite Leishmania species. Existing drugs have limitations due to …

Objective The present study aimed to elucidate the cell death mechanism in Leishmania
donovani upon treatment with KalsomeTM10, a new liposomal amphotericin B …

Green synthesis of silver nanomaterial plays a pivotal role in the growing field of
nanotechnology. Development of anti-parasitic drugs from plant metabolites has been in …

Peptide-based drugs are an attractive class of therapeutic agents, recently recognized by
the pharmaceutical industry. These molecules are currently being used in the development …

Background Visceral leishmaniasis (VL), caused by the protozoan parasite Leishmania
donovani (L. donovani), is the most severe form of leishmaniasis. It is largely responsible for …

The growth and survival of intracellular parasites depends on the availability of extracellular
nutrients. Deprivation of nutrients viz glucose or amino acid alters redox balance in …

The remarkable ability of microorganisms to develop resistance to conventional antibiotics is
one of the biggest challenges that the pharmaceutical industry currently faces. Recent …

Protozoa is a group of microorganisms that cause neglected tropical diseases, such as
malaria, Chagas disease, and Leishmaniasis. Due to the growing demand for new …

Understanding the mechanism that allows the intracellular protozoan parasite Leishmania
donovani (Ld) to respond to reactive oxygen species (ROS) is of increasing therapeutic …