Regulatory mechanisms of exopolysaccharide synthesis and biofilm formation in Streptococcus mutans
T Zheng, M Jing, T Gong, J Yan, X Wang… - Journal of Oral …, 2023 - Taylor & Francis
Background Dental caries is a chronic, multifactorial and biofilm-mediated oral bacterial
infection affecting almost every age group and every geographical region. Streptococcus …
infection affecting almost every age group and every geographical region. Streptococcus …
Antibacterial activities of anthraquinones: structure–activity relationships and action mechanisms
T Qun, T Zhou, J Hao, C Wang, K Zhang, J Xu… - RSC Medicinal …, 2023 - pubs.rsc.org
With the increasing prevalence of untreatable infections caused by antibiotic-resistant
bacteria, the discovery of new drugs from natural products has become a hot research topic …
bacteria, the discovery of new drugs from natural products has become a hot research topic …
Antimicrobial Activity of Cinnamaldehyde on Streptococcus mutans Biofilms
Z He, Z Huang, W Jiang, W Zhou - Frontiers in microbiology, 2019 - frontiersin.org
Streptococcus mutans is considered the most relevant bacteria in the transition of non-
pathogenic commensal oral microbiota to biofilms which contribute to the dental caries …
pathogenic commensal oral microbiota to biofilms which contribute to the dental caries …
[HTML][HTML] Rhein: A novel antibacterial compound against Streptococcus mutans infection
V Folliero, F Dell'Annunziata, E Roscetto… - Microbiological …, 2022 - Elsevier
Streptococcus mutans (S. mutans) is considered the main causative agent of dental caries.
The study aims to evaluate the antimicrobial activity of a natural plant product, pure 4, 5'' …
The study aims to evaluate the antimicrobial activity of a natural plant product, pure 4, 5'' …
Cytotoxicity and antimicrobial action of selected phytochemicals against planktonic and sessile Streptococcus mutans
M Ribeiro, J Malheiro, L Grenho, MH Fernandes… - PeerJ, 2018 - peerj.com
Background Dental caries remains the most prevalent and costly oral infectious disease
worldwide, encouraging the search for new and more effective antimicrobials. Therefore, the …
worldwide, encouraging the search for new and more effective antimicrobials. Therefore, the …
Repeated Exposure of Vancomycin to Vancomycin-Susceptible Staphylococcus aureus (VSSA) Parent Emerged VISA and VRSA Strains with Enhanced Virulence …
A Nguyen, J Roy, JH Kim, KH Yun, W Lee, KK Kim… - Journal of …, 2024 - Springer
The emergence of resistance against the last-resort antibiotic vancomycin in staphylococcal
infections is a serious concern for human health. Although various drug-resistant pathogens …
infections is a serious concern for human health. Although various drug-resistant pathogens …
Design and evaluation of substrate–product analog inhibitors for racemases and epimerases utilizing a 1, 1-proton transfer mechanism
SL Bearne - Methods in Enzymology, 2023 - Elsevier
Racemases and epimerases catalyze the inversion of stereochemistry at asymmetric carbon
atoms to generate stereoisomers that often play important roles in normal and pathological …
atoms to generate stereoisomers that often play important roles in normal and pathological …
[HTML][HTML] Contribution of the murI gene encoding glutamate racemase in the motility and virulence of Ralstonia solanacearum
Bacterial traits for virulence of Ralstonia solanacearum causing lethal wilt in plants were
extensively studied but are not yet fully understood. Other than the known virulence factors …
extensively studied but are not yet fully understood. Other than the known virulence factors …
Significance of Glutamate Racemase for the Viability and Cell Wall Integrity of Streptococcus iniae
Streptococcus iniae is a pathogenic and zoonotic bacterium responsible for human diseases
and mortality of many fish species. Recently, this bacterium has demonstrated an increasing …
and mortality of many fish species. Recently, this bacterium has demonstrated an increasing …
Changes in quaternary structure cause a kinetic asymmetry of glutamate racemase‐catalyzed homocysteic acid racemization
Glutamate racemases (GR) catalyze the racemization of d‐and l‐glutamate and are targets
for the development of antibiotics. We demonstrate that GR from the periodontal pathogen …
for the development of antibiotics. We demonstrate that GR from the periodontal pathogen …