The goal of this review is to provide a perspective on the nature and importance of the
relationship between the circadian and pain systems. We provide: 1) An overview of the …

Despite promising preliminary results in treating fibromyalgia (FM) pain, no neuromodulation
technique has been adopted in clinical practice because of limited efficacy, low response …

Chronic pain patients commonly complain of working memory deficits, but the mechanisms
and brain areas underlying this cognitive impairment remain elusive. The neuronal …

Thalamocortical oscillations are critical for sensory perception. Although pain is known to
disrupt synchrony in thalamocortical oscillations, evidence in the literature is controversial …

The medial prefrontal cortex (mPFC) and the mediodorsal thalamus (MD) form
interconnected neural circuits that are important for spatial cognition and memory, but it is …

Researchers have hypothesized that thalamocortical dysfunction plays a role in
fibromyalgia. The use of low‐frequency sound stimulation to ameliorate thalamocortical …

The role of epigenetics in chronic pain at the supraspinal level is yet to be fully
characterized. DNA histone methylation is crucially regulated by de novo methyltransferases …

Frequent nightly arousals typical for sleep disorders cause daytime fatigue and present
health risks. As such arousals are often short, partial, or occur locally within the brain …

Background Prelimbic medial prefrontal cortex (PL‐mPFC) and nucleus accumbens core
region (NAcc) play an important role in supporting several executive cognitive mechanisms …

Dopamine plays an important role in several forms of synaptic plasticity in the hippocampus,
a crucial brain structure for working memory (WM) functioning. In this study, we evaluated …