In-vivo and ex-vivo optical clearing methods for biological tissues

I Costantini, R Cicchi, L Silvestri, F Vanzi… - Biomedical optics …, 2019 - opg.optica.org
Every optical imaging technique is limited in its penetration depth by scattering occurring in
biological tissues. Possible solutions to overcome this problem consist of limiting the …

Measurement of tissue optical properties in a wide spectral range: a review

IS Martins, HF Silva, EN Lazareva… - Biomedical Optics …, 2023 - opg.optica.org
A distinctive feature of this review is a critical analysis of methods and results of
measurements of the optical properties of tissues in a wide spectral range from deep UV to …

[HTML][HTML] Dense-UNet: a novel multiphoton in vivo cellular image segmentation model based on a convolutional neural network

S Cai, Y Tian, H Lui, H Zeng, Y Wu… - Quantitative imaging in …, 2020 - ncbi.nlm.nih.gov
Background Multiphoton microscopy (MPM) offers a feasible approach for the biopsy in
clinical medicine, but it has not been used in clinical applications due to the lack of efficient …

Hydrogen bound water profiles in the skin influenced by optical clearing molecular agents—Quantitative analysis using confocal Raman microscopy

AY Sdobnov, ME Darvin, J Schleusener… - Journal of …, 2019 - Wiley Online Library
Confocal Raman microscopy has been used to measure depth‐dependent profiles of
porcine skin ex vivo in the high wavenumber region after application of molecular optical …

A simple non-invasive approach toward efficient transdermal drug delivery based on biodegradable particulate system

YI Svenskaya, EA Genina… - … applied materials & …, 2019 - ACS Publications
Transdermal administration via skin appendages enables both localized and systemic drug
delivery, as well as minimizes incidental toxicity. However, the design of an appropriate …

Enhanced ultraviolet spectroscopy by optical clearing for biomedical applications

I Carneiro, S Carvalho, R Henrique… - IEEE Journal of …, 2020 - ieeexplore.ieee.org
In this paper, we describe the combination of ultraviolet (UV) spectroscopy with the optical
clearing technique to induce new tissue windows, evaluate their efficiency, study the …

Skin optical clearing enabled by dissolving hyaluronic acid microneedle patches

M Ouyang, X Wang, Y Fu, G Xie, S Du, Y Li… - International Journal of …, 2022 - Elsevier
Optical imaging and phototherapy are of great significance in the detection, diagnosis, and
therapy of diseases. Depth of light in the skin tissues in optical imaging and phototherapy …

Biophotonics methods for functional monitoring of complications of diabetes mellitus

E Zharkikh, V Dremin, E Zherebtsov… - Journal of …, 2020 - Wiley Online Library
The prevalence of diabetes complications is a significant public health problem with a
considerable economic cost. Thus, the timely diagnosis of complications and prevention of …

A robust ex vivo method to evaluate the diffusion properties of agents in biological tissues

I Carneiro, S Carvalho, R Henrique… - Journal of …, 2019 - Wiley Online Library
A robust method is presented for evaluating the diffusion properties of chemicals in ex vivo
biological tissues. Using this method that relies only on thickness and collimated …

Spectral optical properties of rabbit brain cortex between 200 and 1000 nm

TM Gonçalves, IS Martins, HF Silva, VV Tuchin… - Photochem, 2021 - mdpi.com
The knowledge of the optical properties of biological tissues in a wide spectral range is
highly important for the development of noninvasive diagnostic or treatment procedures. The …