Shining new light on biological systems: luminescent transition metal complexes for bioimaging and biosensing applications

LCC Lee, KKW Lo - Chemical Reviews, 2024 - ACS Publications
Luminescence imaging is a powerful and versatile technique for investigating cell
physiology and pathology in living systems, making significant contributions to life science …

Long-lived emissive probes for time-resolved photoluminescence bioimaging and biosensing

KY Zhang, Q Yu, H Wei, S Liu, Q Zhao… - Chemical …, 2018 - ACS Publications
In this Review article, we systematically summarize the design and applications of various
kinds of long-lived emissive probes for bioimaging and biosensing via time-resolved …

A reaction-based ratiometric fluorescent sensor for the detection of Hg (II) ions in both cells and bacteria

SL Pan, K Li, LL Li, MY Li, L Shi, YH Liu… - Chemical …, 2018 - pubs.rsc.org
A novel reaction-based fluorescent probe (ATC-Hg) was designed and synthesized via the
“covalent assembly” principle, which exhibited excellent selectivity and high sensitivity for …

Strategic Design of Luminescent Rhenium (I), Ruthenium (II), and Iridium (III) Complexes as Activity‐Based Probes for Bioimaging and Biosensing

LCC Lee, KKW Lo - Chemistry–An Asian Journal, 2022 - Wiley Online Library
The rapid development of responsive fluorescent probes has advanced optical imaging for
biological research and biomedical applications. Among different sensing strategies, activity …

Development of a novel lysosome-targeted ruthenium (II) complex for phosphorescence/time-gated luminescence assay of biothiols

Q Gao, W Zhang, B Song, R Zhang, W Guo… - Analytical …, 2017 - ACS Publications
Considering the important roles of biothiols in lysosomes of live organisms, and unique
photophysical/photochemical properties of ruthenium (II) complexes, a novel ruthenium (II) …

Phosphorescence-based ratiometric probes: Design, preparation and applications in sensing, imaging and biomedicine therapy

H Jin, X Jiang, Z Sun, R Gui - Coordination Chemistry Reviews, 2021 - Elsevier
Phosphorescence-based ratiometric probes (PRPs) have multiple advantages from dual-
signal ratiometric output, intrinsic signal built-in correction and long-lived luminescence, and …

Phosphorescent iridium (III) complexes with acyclic diaminocarbene ligands as chemosensors for mercury

AA Eremina, MA Kinzhalov, EA Katlenok… - Inorganic …, 2020 - ACS Publications
A new application for bis (cyclometalated) iridium (III) species containing ancillary acyclic
diaminocarbene ligands, viz. for sensing of mercury (II) ions, is disclosed. A family of bis …

Ratiometric luminescence sensing based on a mixed Ce/Eu metal–organic framework

D Yue, Y Huang, L Zhang, K Jiang, X Zhang… - Journal of Materials …, 2018 - pubs.rsc.org
Ascorbic acid (AA), which is a well-known antioxidant, reacts with reactive oxygen species
(ROS) inside the human body. It is crucial for the proper functioning of living organisms …

Iridium (III) Complex‐Based Activatable Probe for Phosphorescent/Time‐Gated Luminescent Sensing and Imaging of Cysteine in Mitochondria of Live Cells and …

Z Du, R Zhang, B Song, W Zhang… - … A European Journal, 2019 - Wiley Online Library
This study reports an activatable iridium (III) complex probe for phosphorescence/time‐gated
luminescence detection of cysteine (Cys) in vitro and in vivo. The probe,[Ir (ppy) 2 (NTY …

Dual-targetable fluorescent probe for mapping the fluctuation of peroxynitrite in drug-induced liver injury model

Y Wang, Y Liu, X Song, Y Feng, C Jing, G Zhang… - … Acta Part A: Molecular …, 2023 - Elsevier
Drug-induced liver injury (DILI) is one of the most common and serious adverse drug
reactions which can cause acute liver failure or even death in severe cases. With the …