Ocular drug delivery has constantly challenged ophthalmologists and drug delivery
scientists due to various anatomical and physiological barriers. Static and dynamic ocular …

Genome-editing technologies have ushered in a new era in gene therapy, providing novel
therapeutic strategies for a wide range of diseases, including both genetic and nongenetic …

CRISPR-Cas13 nucleases are programmable RNA-targeting effectors that can silence gene
expression in a transient manner. Recent iterations of Cas13 nucleases are compact for …

In contrast to conventional therapies that require repeated dosing, gene therapy can treat
diseases by correcting defective genes after a single transfection and achieving cascade …

Adaptive optics (AO) imaging enables direct, objective assessments of retinal cells.
Applications of AO show great promise in advancing our understanding of the etiology of …

Inherited forms of blindness and deafness are highly prevalent and severe conditions that
significantly impact the lives of millions of people worldwide. The lack of therapeutic options …

Adenosine deaminases acting on RNA (ADARs) are endogenous enzymes catalyzing the
deamination of adenosines to inosines, which are then read as guanosines during …

RNA editing holds great promise for the therapeutic correction of pathogenic, single
nucleotide variants (SNV) in the human transcriptome since it does not risk creating …

Retinitis pigmentosa (RP) is a progressive inherited retinal dystrophy, characterized by the
degeneration of photoreceptors, presenting as a rod-cone dystrophy. Approximately 20-30 …

Dependence on mobile phone information in the Internet era is a crucial issue, and
psychological perception and personalized and accurate pushing significantly impact this …