[PDF][PDF] VEGF in signaling and disease: beyond discovery and development

RS Apte, DS Chen, N Ferrara - Cell, 2019 - cell.com
The discovery of vascular endothelial-derived growth factor (VEGF) has revolutionized our
understanding of vasculogenesis and angiogenesis during development and physiological …

[HTML][HTML] Diabetic retinopathy: current understanding, mechanisms, and treatment strategies

EJ Duh, JK Sun, AW Stitt - JCI insight, 2017 - ncbi.nlm.nih.gov
Diabetic retinopathy (DR) causes significant visual loss on a global scale. Treatments for the
vision-threatening complications of diabetic macular edema (DME) and proliferative diabetic …

Neurodegeneration in diabetic retinopathy: does it really matter?

R Simó, AW Stitt, TW Gardner - Diabetologia, 2018 - Springer
The concept of diabetic retinopathy as a microvascular disease has evolved, in that it is now
considered a more complex diabetic complication in which neurodegeneration plays a …

The progress in understanding and treatment of diabetic retinopathy

AW Stitt, TM Curtis, M Chen, RJ Medina… - Progress in retinal and …, 2016 - Elsevier
Diabetic retinopathy is the most frequently occurring complication of diabetes mellitus and
remains a leading cause of vision loss globally. Its aetiology and pathology have been …

The evolving treatment of diabetic retinopathy

SE Mansour, DJ Browning, K Wong… - Clinical …, 2020 - Taylor & Francis
Purpose To review the current therapeutic options for the management of diabetic
retinopathy (DR) and diabetic macular edema (DME) and examine the evidence for …

Photoreceptor cells and RPE contribute to the development of diabetic retinopathy

D Tonade, TS Kern - Progress in retinal and eye research, 2021 - Elsevier
Diabetic retinopathy (DR) is a leading cause of blindness. It has long been regarded as
vascular disease, but work in the past years has shown abnormalities also in the neural …

Neurodegeneration in the diabetic eye: new insights and therapeutic perspectives

R Simo, C Hernández - Trends in Endocrinology & Metabolism, 2014 - cell.com
Diabetic retinopathy (DR), one of the leading causes of preventable blindness, has been
considered a microcirculatory disease of the retina. However, there is emerging evidence to …

[HTML][HTML] Biomarkers in diabetic retinopathy

AJ Jenkins, MV Joglekar, AA Hardikar… - The review of diabetic …, 2015 - ncbi.nlm.nih.gov
There is a global diabetes epidemic correlating with an increase in obesity. This coincidence
may lead to a rise in the prevalence of type 2 diabetes. There is also an as yet unexplained …

Neurovascular unit in diabetic retinopathy: pathophysiological roles and potential therapeutical targets

S Nian, ACY Lo, Y Mi, K Ren, D Yang - Eye and Vision, 2021 - Springer
Diabetic retinopathy (DR), one of the common complications of diabetes, is the leading
cause of visual loss in working-age individuals in many industrialized countries. It has been …

Early detection of diabetic retinopathy

H Safi, S Safi, A Hafezi-Moghadam… - Survey of ophthalmology, 2018 - Elsevier
Diabetic retinopathy (DR) is a primary cause of visual impairment worldwide. Diabetes
mellitus may be associated with ophthalmoscopically nonvisible neurovascular damage that …