[HTML][HTML] Recent advances on biological activities and structural modifications of dehydroabietic acid
M Hao, J Xu, H Wen, J Du, S Zhang, M Lv, H Xu - Toxins, 2022 - mdpi.com
Dehydroabietic acid is a tricyclic diterpenoid resin acid isolated from rosin. Dehydroabietic
acid and its derivatives showed lots of medical and agricultural bioactivities, such as …
acid and its derivatives showed lots of medical and agricultural bioactivities, such as …
[HTML][HTML] Synthesis and antiproliferative activity of novel dehydroabietic acid-chalcone hybrids
S Grigoropoulou, D Manou, AI Antoniou, A Tsirogianni… - Molecules, 2022 - mdpi.com
Dehydroabietic Acid (DHA, 1) derivatives are known for their antiproliferative properties,
among others. In the context of this work, DHA was initially modified to two key intermediates …
among others. In the context of this work, DHA was initially modified to two key intermediates …
[HTML][HTML] Extracts from Argentinian native plants reverse fluconazole resistance in Candida species by inhibiting the efflux transporters Mdr1 and Cdr1
F Gil, J Laiolo, B Bayona-Pacheco, RD Cannon… - … medicine and therapies, 2022 - Springer
Background The development of multidrug resistance (MDR) associated with the
overexpression of the efflux transporters Mdr1 and Cdr1 in Candida species impedes …
overexpression of the efflux transporters Mdr1 and Cdr1 in Candida species impedes …
[HTML][HTML] Inhibition of MurA Enzyme from Escherichia coli and Staphylococcus aureus by Diterpenes from Lepechinia meyenii and Their Synthetic Analogs
M Funes Chabán, M Hrast, R Frlan, DG Graikioti… - Antibiotics, 2021 - mdpi.com
Enzymes MurA and MurF, involved in bacterial cell wall synthesis, have been validated as
targets for the discovery of novel antibiotics. A panel of plant-origin antibacterial diterpenes …
targets for the discovery of novel antibiotics. A panel of plant-origin antibacterial diterpenes …
[HTML][HTML] The thiophene α-terthienylmethanol isolated from Tagetes minuta inhibits angiogenesis by targeting protein kinase C isozymes α and β2
MC Llorens de los Ríos, PA Lanza… - Frontiers in …, 2022 - frontiersin.org
Background: Tumor angiogenesis is considered as a crucial pathologic feature of cancer
with a key role in multidrug resistance (MDR). Adverse effects of the currently available …
with a key role in multidrug resistance (MDR). Adverse effects of the currently available …