Hereditary diffuse gastric cancer (HDGC) is an autosomal dominant cancer syndrome that is
characterised by a high prevalence of diffuse gastric cancer and lobular breast cancer. It is …

This guideline presents recommendations for the management of patients with hereditary
gastrointestinal cancer syndromes. The initial assessment is the collection of a family history …

Importance E-cadherin (CDH1) is a cancer predisposition gene mutated in families meeting
clinically defined hereditary diffuse gastric cancer (HDGC). Reliable estimates of cancer risk …

Familial gastric cancer comprises at least three major syndromes: hereditary diffuse gastric
cancer, gastric adenocarcinoma and proximal polyposis of the stomach, and familial …

Knowledge of genetic susceptibility to gastrointestinal cancers is constantly evolving with
identification of new genes. Similarly, a better understanding of the genotype/phenotype …

Gastric cancer remains one of the deadly diseases with poor prognosis. New classification
of gastric cancers based on histologic features, genotypes and molecular phenotypes helps …

Gastric cancer remains highly prevalent and accounts for a notable proportion of global
cancer mortality. This cancer is also associated with poor survival rates. Understanding the …

Skin‐based wearable devices have a great potential that could result in a revolutionary
approach to health monitoring and diagnosing disease. With continued innovation and …

This review is dedicated to E-cadherin, a calcium-dependent cell-cell adhesion molecule
with pivotal roles in epithelial cell behavior, tissue formation, and suppression of cancer. As …

We review the role of cadherins and cadherin-related proteins in human cancer. Cellular
and animal models for human cancer are also dealt with whenever appropriate. E-cadherin …