Pazopanib versus sunitinib in metastatic renal-cell carcinoma
Background Pazopanib and sunitinib provided a progression-free survival benefit, as
compared with placebo or interferon, in previous phase 3 studies involving patients with …
compared with placebo or interferon, in previous phase 3 studies involving patients with …
Pazopanib in locally advanced or metastatic renal cell carcinoma: results of a randomized phase III trial
CN Sternberg, ID Davis, J Mardiak… - Journal of clinical …, 2010 - ascopubs.org
Purpose Pazopanib is an oral angiogenesis inhibitor targeting vascular endothelial growth
factor receptor, platelet-derived growth factor receptor, and c-Kit. This randomized, double …
factor receptor, platelet-derived growth factor receptor, and c-Kit. This randomized, double …
[HTML][HTML] Prognostic and predictive value of VHL gene alteration in renal cell carcinoma: a meta-analysis and review
BJ Kim, JH Kim, HS Kim, DY Zang - Oncotarget, 2017 - ncbi.nlm.nih.gov
Abstract The von Hippel-Lindau (VHL) gene is often inactivated in sporadic renal cell
carcinoma (RCC) by mutation or promoter hypermethylation. The prognostic or predictive …
carcinoma (RCC) by mutation or promoter hypermethylation. The prognostic or predictive …
[HTML][HTML] A randomised, double-blind phase III study of pazopanib in patients with advanced and/or metastatic renal cell carcinoma: final overall survival results and …
BACKGROUND: In this randomised phase III study (VEG105192; NCT00334282),
pazopanib previously demonstrated statistically and clinically meaningful improvement of …
pazopanib previously demonstrated statistically and clinically meaningful improvement of …
Molecular pathology of renal oncocytoma: a review
MV Yusenko - International Journal of Urology, 2010 - Wiley Online Library
Differentiating renal oncocytoma from its renal cell carcinoma (RCC) mimics, particularly
chromophobe RCC, can be difficult, especially when limited tissue is available for evaluation …
chromophobe RCC, can be difficult, especially when limited tissue is available for evaluation …
Case–control study on renal cell cancer and occupational exposure to trichloroethylene. Part II: epidemiological aspects
B Charbotel, J Fevotte, M Hours… - The Annals of …, 2006 - academic.oup.com
To test the effect of the exposure to trichloroethylene (TCE) on renal cell cancer (RCC) risk, a
case–control study was performed in the Arve Valley (France), a geographic area with a …
case–control study was performed in the Arve Valley (France), a geographic area with a …
NFκB-mediated cyclin D1 expression by microRNA-21 influences renal cancer cell proliferation
A Bera, N Ghosh-Choudhury, N Dey, F Das… - Cellular signalling, 2013 - Elsevier
MicroRNAs regulate post-transcriptomic landscape in many tumors including renal cell
carcinoma. We have recently shown significantly increased expression of miR-21 in renal …
carcinoma. We have recently shown significantly increased expression of miR-21 in renal …
Characteristics and outcomes of tumors arising from the distal nephron
OBJECTIVE: To compare the characteristics and predictors of cancer-specific survival (CSS)
of 2 rare distal nephron tumors—medullary renal cell carcinoma (MRCC) and collecting duct …
of 2 rare distal nephron tumors—medullary renal cell carcinoma (MRCC) and collecting duct …
Activation of HIF2α in kidney proximal tubule cells causes abnormal glycogen deposition but not tumorigenesis
L Fu, G Wang, MM Shevchuk, DM Nanus, LJ Gudas - Cancer research, 2013 - AACR
Renal cell carcinoma (RCC) is the most common primary cancer arising from the kidney in
adults, with clear cell renal cell carcinoma (ccRCC) representing approximately 75% of all …
adults, with clear cell renal cell carcinoma (ccRCC) representing approximately 75% of all …
Comprehensive study of three novel cases of TFEB‐amplified renal cell carcinoma and review of the literature: Evidence for a specific entity with poor outcome
L Mendel, D Ambrosetti, Y Bodokh… - Genes …, 2018 - Wiley Online Library
The first case of TFEB‐amplified renal cell carcinoma was published in 2014. Since then, 29
additional cases have been described. The prognostic and therapeutic implications of this …
additional cases have been described. The prognostic and therapeutic implications of this …