The study of biological systems in a holistic manner (systems biology) is increasingly being
viewed as a necessity to provide qualitative and quantitative descriptions of the emergent …

Metabolomics is the discipline where endogenous and exogenous metabolites are
assessed, identified and quantified in different biological samples. Metabolites are crucial …

Cerebrospinal fluid is vital for normal brain function. Changes to the composition, flow, or
pressure can cause a variety of neurological symptoms and signs. Equally, disorders of …

Idiopathic intracranial hypertension is a disease of unknown aetiology, typically affecting
young obese women, producing a syndrome of increased intracranial pressure without …

Objective Inflammatory arthritis is associated with systemic manifestations including
alterations in metabolism. We used nuclear magnetic resonance (NMR) spectroscopy …

Objective Anti–tumor necrosis factor (anti‐TNF) therapies are highly effective in rheumatoid
arthritis (RA) and psoriatic arthritis (PsA), but a significant number of patients exhibit only a …

Since antiquity, humans have used body fluids like saliva, urine and sweat for the diagnosis
of diseases. The amount, color and smell of body fluids are still used in many traditional …

BACKGROUND. Our goal was to identify changes in the metabolome in multiple sclerosis
(MS) and how vitamin D supplementation alters metabolic profiles in MS patients and …

Nuclear magnetic resonance (NMR) and Mass Spectroscopy (MS) are the two most common
spectroscopic analytical techniques employed in metabolomics. The large spectral datasets …

Multiple sclerosis (MS) is an inflammatory demyelinating disease of the nervous system that
primarily affects young adults. Although the exact etiology of the disease remains obscure, it …