Pseudomonas aeruginosa is a metabolically versatile bacterium that can cause a wide
range of severe opportunistic infections in patients with serious underlying medical …

Acute respiratory distress syndrome (ARDS) is a devastating disease with distinct
pathological stages. Fundamental to ARDS is the acute onset of lung inflammation as a part …

Pseudomonas aeruginosa is an important pathogen causing a wide range of acute and
chronic infections. P. aeruginosa rarely causes infection in the normal host, but is an efficient …

The potential therapeutic value of cell-based therapy with mesenchymal stem cells (MSC)
has been reported in mouse models of polymicrobial peritoneal sepsis. However, the …

Lung infections caused by the opportunistic pathogen Pseudomonas aeruginosa can
present as a spectrum of clinical entities from a rapidly fatal pneumonia in a neutropenic …

Alveolar macrophages are a unique type of mononuclear phagocytes that populate the
external surface of the lung cavity. Early studies have suggested that alveolar macrophages …

Bone marrow transplantation (BMT) is the treatment of choice for many leukemias, solid
tumors, and metabolic diseases. The field of bone marrow research is highly dependent on …

Sepsis results in a state of relative immunosuppression, rendering critically ill patients
susceptible to secondary infections and increased mortality. Monocytes isolated from septic …

Macrophages are a primary immune cell involved in inflammation, and their cell plasticity
allows for transition from an inflammatory to a reparative phenotype and is critical for normal …

The body is exposed to foreign pathogens every day, but remarkably, most pathogens are
effectively cleared by the innate immune system without the need to invoke the adaptive …