Acute myocardial infarction (MI) inflicts massive injury to the coronary microcirculation
leading to vascular disintegration and capillary rarefication in the infarct region. Tissue …

The vasculature ensures optimal delivery of nutrients and oxygen throughout the body, and
to achieve this function it must continually adapt to varying tissue demands. Newly formed …

Macrophages (Mφs) produce factors that participate in cardiac repair and remodeling after
myocardial infarction (MI); however, how these factors crosstalk with other cell types …

A plethora of in vitro models have been the focus of intense research to mimic the native
physiological system more accurately. Among them, organ-on-a-chip or microfluidic devices …

Tissue imaging in 3D using visible light is limited and various clearing techniques were
developed to increase imaging depth, but none provides universal solution for all tissues at …

The rising incidence of non-ST-segment elevation myocardial infarction (NSTEMI) and
associated long-term high mortality constitutes an urgent clinical issue. Unfortunately, the …

Introduction: Removal of poorly perfused capillaries by pruning contributes to remodeling
the microvasculature to optimize oxygen and nutrient delivery. Blood flow drives this process …

Porphyromonas gingivalis and Filifactor alocis are fastidious oral pathogens and etiological
agents associated with chronic periodontitis. Although previous studies showed increased …

Abstract Insulin-like growth factor-1 (IGF-1) has demonstrated beneficial effects after
myocardial infarction (MI). Microencapsulation of IGF-1 could potentially improve results. We …

Coronary heart diseases are of high relevance for health care systems in developed
countries regarding patient numbers and costs. Disappointingly, the enormous effort put into …