Increases in calorie consumption and sedentary lifestyles are fuelling a global pandemic of
cardiometabolic diseases, including coronary artery disease, diabetes mellitus …

Reactive oxygen species (ROS) play an essential role in regulating various physiological
functions of living organisms. The intrinsic biochemical properties of ROS, which underlie …

Dr Irvine Page proposed the Mosaic Theory of Hypertension in the 1940s advocating that
hypertension is the result of many factors that interact to raise blood pressure and cause end …

Cells of the vascular wall are exquisitely sensitive to changes in their mechanical
environment. In healthy vessels, mechanical forces regulate signaling and gene expression …

As one of the most widely investigated matrix metalloproteinases (MMPs), MMP-9 is a
significant protease which plays vital roles in many biological processes. MMP-9 can cleave …

Acute ischemic stroke is a common cause of morbidity and mortality worldwide.
Thrombolysis with recombinant tissue plasminogen activator and endovascular …

Free radicals contain one or more unpaired electrons in their valence shell, thus making
them unstable, short-lived, and highly reactive species. Excessive generation of these free …

Several studies indicated how dietary patterns that were obtained from nutritional cluster
analysis can predict disease risk or mortality. Low-grade chronic inflammation represents a …

Free radicals and other oxidants have gained importance in the field of biology due to their
central role in various physiological conditions as well as their implication in a diverse range …

Metabolic syndrome, which includes diabetes and obesity, is one of the most widespread
medical conditions. It induces systemic inflammation, causing far reaching effects on the …