The GATA family of transcription factors consists of six proteins (GATA1-6) which are
involved in a variety of physiological and pathological processes. GATA1/2/3 are required …

Previous work has demonstrated that lineage-specific transcription factors play essential
roles in red blood cell development. More recent studies have shown that these factors …

Transcription factor GATA-1 reprograms immature myeloid cells to three different
hematopoietic lineages-erythroid cells, megakaryocytes, and eosinophils. GATA-1 is …

Transcription factor GATA‐1 is essential for red blood cell maturation and, therefore, for
survival of developing mouse embryos. GATA‐1 is also expressed in megakaryocytes, mast …

Members of the GATA family of transcription factors, which are related by a high degree of
amino acid sequence identity within their zinc finger DNA-binding domains, each show …

The development of mature blood cells of distinct lineages, from the hematopoietic stem
cells (HSCs), involves a progressive restriction of differentiation potential and the …

GATA–3 is one member of a growing family of related transcription factors which share a
strongly conserved expression pattern in all vertebrate organisms. In order to elucidate …

During vertebrate embryonic development, the paraxial mesoderm is subdivided into
metameric subunits called somites. The arrangement and cranio-caudal polarity of the …

Transcriptional networks orchestrate complex developmental processes. Such networks are
commonly instigated by master regulators of development. Considerable progress has been …

We describe experiments which show that: 1) two previously identified members of the
GATA family of transcription factors (both of which were originally called GATA-4) …