Post-stroke depression: mechanisms and pharmacological treatment
Depression, the most frequent psychiatric disorder following ischaemic stroke, negatively
affects survivals' functional outcome, response to rehabilitation and quality of life …
affects survivals' functional outcome, response to rehabilitation and quality of life …
Insulin resistance and oxidative stress in the brain: what's new?
M Maciejczyk, E Żebrowska, A Chabowski - International journal of …, 2019 - mdpi.com
The latest studies have indicated a strong relationship between systemic insulin resistance
(IR) and higher incidence of neurodegeneration, dementia, and mild cognitive impairment …
(IR) and higher incidence of neurodegeneration, dementia, and mild cognitive impairment …
The neurobiology of depression: an integrated overview from biological theories to clinical evidence
Depressive disorders are heterogeneous diseases, and the complexity of symptoms has led
to the formulation of several aethiopathological hypotheses. This heterogeneity may account …
to the formulation of several aethiopathological hypotheses. This heterogeneity may account …
Molecular aspects of depression: a review from neurobiology to treatment
GRV Boas, RB de Lacerda, MM Paes, P Gubert… - European journal of …, 2019 - Elsevier
Major depressive disorder (MDD), also known as unipolar depression, is one of the leading
causes of disability and disease worldwide. The signs and symptoms are low self‑esteem …
causes of disability and disease worldwide. The signs and symptoms are low self‑esteem …
Incretin-based drugs as potential therapy for neurodegenerative diseases: current status and perspectives
Alzheimer's disease (AD) and Parkinson's disease (PD) are the most frequent
neurodegenerative disorders. Despite their pathophysiological and clinical differences, they …
neurodegenerative disorders. Despite their pathophysiological and clinical differences, they …
Redox balance, antioxidant defense, and oxidative damage in the hypothalamus and cerebral cortex of rats with high fat diet‐induced insulin resistance
M Maciejczyk, E Żebrowska, A Zalewska… - Oxidative medicine …, 2018 - Wiley Online Library
Oxidative stress is a key pathogenic factor in both neurogenerative and metabolic diseases.
However, its contribution in the brain complications of insulin resistance is still not well …
However, its contribution in the brain complications of insulin resistance is still not well …
Targeted placental deletion of OGT recapitulates the prenatal stress phenotype including hypothalamic mitochondrial dysfunction
CL Howerton, TL Bale - Proceedings of the National …, 2014 - National Acad Sciences
Maternal stress is a key risk factor in neurodevelopmental disorders, which often have a sex
bias in severity and prevalence. We previously identified O-GlcNAc transferase (OGT) as a …
bias in severity and prevalence. We previously identified O-GlcNAc transferase (OGT) as a …
A comprehensive review on bioavailability, safety and antidepressant potential of natural bioactive components from tea
J Shao, Y Wei, X Wei - Food Research International, 2022 - Elsevier
Depression is a global public health issue with high morbidity and mortality, which tends to
cause fatigue, inability to concentrate, insomnia, and loss of appetite, especially represented …
cause fatigue, inability to concentrate, insomnia, and loss of appetite, especially represented …
High protein diet induces oxidative stress in rat cerebral cortex and hypothalamus
E Żebrowska, M Maciejczyk… - International journal of …, 2019 - mdpi.com
This is the first study to analyze the impact of high protein diet (HPD) on antioxidant defense,
redox status, as well as oxidative damage on both a local and systemic level. Male Wistar …
redox status, as well as oxidative damage on both a local and systemic level. Male Wistar …
Brain cortex mitochondrial bioenergetics in synaptosomes and non-synaptic mitochondria during aging
S Lores-Arnaiz, P Lombardi, AG Karadayian… - Neurochemical …, 2016 - Springer
Alterations in mitochondrial bioenergetics have been associated with brain aging. In order to
evaluate the susceptibility of brain cortex synaptosomes and non-synaptic mitochondria to …
evaluate the susceptibility of brain cortex synaptosomes and non-synaptic mitochondria to …