A review of Dengvaxia®: development to deployment

SJ Thomas, IK Yoon - Human vaccines & immunotherapeutics, 2019 - Taylor & Francis
Dengue is the world's most prevalent and important arboviral disease. More than 50% of the
world's population lives at daily risk of infection and it is estimated more than 95 million …

[HTML][HTML] Dengue vaccine: recommendations of the advisory committee on immunization practices, United States, 2021

G Paz-Bailey - MMWR. Recommendations and Reports, 2021 - cdc.gov
Dengue is a vectorborne infectious disease caused by dengue viruses (DENVs), which are
predominantly transmitted by Aedes aegypti and Aedes albopictus mosquitos. Dengue is …

Vaccines licensed and in clinical trials for the prevention of dengue

J Torresi, G Ebert, M Pellegrini - Human vaccines & …, 2017 - Taylor & Francis
Dengue has become a major global public health threat with almost half of the world's
population living in at-risk areas. Vaccination would likely represent an effective strategy for …

Field- and clinically derived estimates of Wolbachia-mediated blocking of dengue virus transmission potential in Aedes aegypti mosquitoes

LB Carrington, BCN Tran, NTH Le… - Proceedings of the …, 2018 - National Acad Sciences
The w Mel strain of Wolbachia can reduce the permissiveness of Aedes aegypti mosquitoes
to disseminated arboviral infections. Here, we report that w Mel-infected Ae. aegypti (Ho Chi …

Evaluation of the extended efficacy of the Dengvaxia vaccine against symptomatic and subclinical dengue infection

H Salje, MT Alera, MN Chua, T Hunsawong, D Ellison… - Nature medicine, 2021 - nature.com
More than half of the world's population lives in areas at risk for dengue virus infection. A
vaccine will be pivotal to controlling spread, however, the only licensed vaccine, Dengvaxia …

Safety issues from a Phase 3 clinical trial of a live-attenuated chimeric yellow fever tetravalent dengue vaccine

SB Halstead - Human vaccines & immunotherapeutics, 2018 - Taylor & Francis
ABSTRACT A tetravalent live-attenuated 3-dose vaccine composed of chimeras of yellow
fever 17D and the four dengue viruses (CYD, also called Dengvaxia) completed phase 3 …

Anti-dengue vaccines: from development to clinical trials

JR Pinheiro-Michelsen, RSO Souza… - Frontiers in …, 2020 - frontiersin.org
Dengue Virus (DENV) is an arbovirus (arthropod-borne virus). Four serotypes of DENV are
responsible for the infectious disease called dengue that annually affects nearly 400 million …

Asymptomatic dengue infection rate: A systematic literature review

O De Santis, N Bouscaren, A Flahault - Heliyon, 2023 - cell.com
Objectives Dengue infection is spreading worldwide. The clinical spectrum is broad and
includes asymptomatic infections. This review provides an overview of the different …

A recombinant live attenuated tetravalent vaccine for the prevention of dengue

B Guy, F Noriega, RL Ochiai, M L'azou… - Expert review of …, 2017 - Taylor & Francis
Introduction: Dengue is an important and still growing public health problem associated with
substantial morbidity, as well as significant social and economic impact. The present review …

[HTML][HTML] Cost-effectiveness of dengue vaccination in ten endemic countries

W Zeng, YA Halasa-Rappel, N Baurin, L Coudeville… - Vaccine, 2018 - Elsevier
Following publication of results from two phase-3 clinical trials in 10 countries or territories,
endemic countries began licensing the first dengue vaccine in 2015. Using a published …