Deep brain stimulation: current challenges and future directions

AM Lozano, N Lipsman, H Bergman, P Brown… - Nature Reviews …, 2019 - nature.com
The clinical use of deep brain stimulation (DBS) is among the most important advances in
the clinical neurosciences in the past two decades. As a surgical tool, DBS can directly …

Harmonizing the neurobiology and treatment of obsessive-compulsive disorder

WK Goodman, EA Storch… - American Journal of …, 2021 - Am Psychiatric Assoc
Obsessive-compulsive disorder (OCD) is a common, chronic, and oftentimes disabling
disorder. The only established first-line treatments for OCD are exposure and response …

Non-invasive temporal interference electrical stimulation of the human hippocampus

IR Violante, K Alania, AM Cassarà, E Neufeld… - Nature …, 2023 - nature.com
Deep brain stimulation (DBS) via implanted electrodes is used worldwide to treat patients
with severe neurological and psychiatric disorders. However, its invasiveness precludes …

[HTML][HTML] Noninvasive deep brain stimulation via temporally interfering electric fields

N Grossman, D Bono, N Dedic, SB Kodandaramaiah… - cell, 2017 - cell.com
We report a noninvasive strategy for electrically stimulating neurons at depth. By delivering
to the brain multiple electric fields at frequencies too high to recruit neural firing, but which …

A fronto–striato–subthalamic–pallidal network for goal-directed and habitual inhibition

M Jahanshahi, I Obeso, JC Rothwell… - Nature Reviews …, 2015 - nature.com
Classically, the basal ganglia have been considered to have a role in producing habitual
and goal-directed behaviours. In this article, we review recent evidence that expands this …

Canadian clinical practice guidelines for the management of anxiety, posttraumatic stress and obsessive-compulsive disorders

MA Katzman, P Bleau, P Blier, P Chokka, K Kjernisted… - BMC psychiatry, 2014 - Springer
Background Anxiety and related disorders are among the most common mental disorders,
with lifetime prevalence reportedly as high as 31%. Unfortunately, anxiety disorders are …

Mechanisms of deep brain stimulation

TM Herrington, JJ Cheng… - Journal of …, 2016 - journals.physiology.org
Deep brain stimulation (DBS) is widely used for the treatment of movement disorders
including Parkinson's disease, essential tremor, and dystonia and, to a lesser extent, certain …

A randomized sham-controlled trial of deep brain stimulation of the ventral capsule/ventral striatum for chronic treatment-resistant depression

DD Dougherty, AR Rezai, LL Carpenter… - Biological …, 2015 - Elsevier
Background Multiple open-label trials of deep brain stimulation (DBS) for treatment-resistant
depression (TRD), including those targeting the ventral capsule/ventral striatum target, have …

[HTML][HTML] Deep brain stimulation for depression

M Figee, P Riva-Posse, KS Choi, L Bederson… - …, 2022 - Elsevier
Deep brain stimulation has been extensively studied as a therapeutic option for treatment-
resistant depression (TRD). DBS across different targets is associated with on average 60 …

Efficacy of deep brain stimulation for treatment-resistant obsessive-compulsive disorder: systematic review and meta-analysis

R Gadot, R Najera, S Hirani, A Anand… - Journal of Neurology …, 2022 - jnnp.bmj.com
Deep brain stimulation (DBS) is an established and growing intervention for treatment-
resistant obsessive-compulsive disorder (TROCD). We assessed current evidence on the …