Deep brain stimulation: current challenges and future directions
The clinical use of deep brain stimulation (DBS) is among the most important advances in
the clinical neurosciences in the past two decades. As a surgical tool, DBS can directly …
the clinical neurosciences in the past two decades. As a surgical tool, DBS can directly …
Harmonizing the neurobiology and treatment of obsessive-compulsive disorder
WK Goodman, EA Storch… - American Journal of …, 2021 - Am Psychiatric Assoc
Obsessive-compulsive disorder (OCD) is a common, chronic, and oftentimes disabling
disorder. The only established first-line treatments for OCD are exposure and response …
disorder. The only established first-line treatments for OCD are exposure and response …
Non-invasive temporal interference electrical stimulation of the human hippocampus
Deep brain stimulation (DBS) via implanted electrodes is used worldwide to treat patients
with severe neurological and psychiatric disorders. However, its invasiveness precludes …
with severe neurological and psychiatric disorders. However, its invasiveness precludes …
[HTML][HTML] Noninvasive deep brain stimulation via temporally interfering electric fields
We report a noninvasive strategy for electrically stimulating neurons at depth. By delivering
to the brain multiple electric fields at frequencies too high to recruit neural firing, but which …
to the brain multiple electric fields at frequencies too high to recruit neural firing, but which …
A fronto–striato–subthalamic–pallidal network for goal-directed and habitual inhibition
M Jahanshahi, I Obeso, JC Rothwell… - Nature Reviews …, 2015 - nature.com
Classically, the basal ganglia have been considered to have a role in producing habitual
and goal-directed behaviours. In this article, we review recent evidence that expands this …
and goal-directed behaviours. In this article, we review recent evidence that expands this …
Canadian clinical practice guidelines for the management of anxiety, posttraumatic stress and obsessive-compulsive disorders
MA Katzman, P Bleau, P Blier, P Chokka, K Kjernisted… - BMC psychiatry, 2014 - Springer
Background Anxiety and related disorders are among the most common mental disorders,
with lifetime prevalence reportedly as high as 31%. Unfortunately, anxiety disorders are …
with lifetime prevalence reportedly as high as 31%. Unfortunately, anxiety disorders are …
Mechanisms of deep brain stimulation
TM Herrington, JJ Cheng… - Journal of …, 2016 - journals.physiology.org
Deep brain stimulation (DBS) is widely used for the treatment of movement disorders
including Parkinson's disease, essential tremor, and dystonia and, to a lesser extent, certain …
including Parkinson's disease, essential tremor, and dystonia and, to a lesser extent, certain …
A randomized sham-controlled trial of deep brain stimulation of the ventral capsule/ventral striatum for chronic treatment-resistant depression
Background Multiple open-label trials of deep brain stimulation (DBS) for treatment-resistant
depression (TRD), including those targeting the ventral capsule/ventral striatum target, have …
depression (TRD), including those targeting the ventral capsule/ventral striatum target, have …
[HTML][HTML] Deep brain stimulation for depression
Deep brain stimulation has been extensively studied as a therapeutic option for treatment-
resistant depression (TRD). DBS across different targets is associated with on average 60 …
resistant depression (TRD). DBS across different targets is associated with on average 60 …
Efficacy of deep brain stimulation for treatment-resistant obsessive-compulsive disorder: systematic review and meta-analysis
Deep brain stimulation (DBS) is an established and growing intervention for treatment-
resistant obsessive-compulsive disorder (TROCD). We assessed current evidence on the …
resistant obsessive-compulsive disorder (TROCD). We assessed current evidence on the …