The bidirectional relationship between sleep and inflammation links traumatic brain injury and Alzheimer's disease
TRF Green, JB Ortiz, S Wonnacott… - Frontiers in …, 2020 - frontiersin.org
Traumatic brain injury (TBI) and Alzheimer's disease (AD) are diseases during which the fine-
tuned autoregulation of the brain is lost. Despite the stark contrast in their causal …
tuned autoregulation of the brain is lost. Despite the stark contrast in their causal …
Traumatic brain injury and the pathways to cerebral tau accumulation
Tau is a protein that has received national mainstream recognition for its potential negative
impact to the brain. This review succinctly provides information on the structure of tau and its …
impact to the brain. This review succinctly provides information on the structure of tau and its …
LncRNA-Meg3 promotes Nlrp3-mediated microglial inflammation by targeting miR-7a-5p
J Meng, T Ding, Y Chen, T Long, Q Xu, W Lian… - International …, 2021 - Elsevier
Recent studies have identified neuroinflammation as a significant contributor to the
pathological process of traumatic brain injury (TBI) and as a potentially effective target for …
pathological process of traumatic brain injury (TBI) and as a potentially effective target for …
The importance of including both sexes in preclinical sleep studies and analyses
A significant effort in biomedical sciences has been made to examine relationships between
sex and the mechanisms underlying various disease states and behaviors, including sleep …
sex and the mechanisms underlying various disease states and behaviors, including sleep …
Sex-dependent pathology in the HPA axis at a sub-acute period after experimental traumatic brain injury
CE Bromberg, AM Condon, SW Ridgway… - Frontiers in …, 2020 - frontiersin.org
Over 2.8 million traumatic brain injuries (TBIs) are reported in the United States annually, of
which, over 75% are mild TBIs with diffuse axonal injury (DAI) as the primary pathology. TBI …
which, over 75% are mild TBIs with diffuse axonal injury (DAI) as the primary pathology. TBI …
Sex specific effects of buprenorphine on adult hippocampal neurogenesis and behavioral outcomes during the acute phase after pediatric traumatic brain injury in …
I Davila-Valencia, M Saad, G Olthoff, M Faulkner… - …, 2024 - Elsevier
Traumatic brain injury (TBI) in children often causes cognitive and mental dysfunctions, as
well as acute and chronic pain. Adult hippocampal neurogenesis plays a key role in …
well as acute and chronic pain. Adult hippocampal neurogenesis plays a key role in …
Deplete and repeat: microglial CSF1R inhibition and traumatic brain injury
R Boland, ON Kokiko-Cochran - Frontiers in Cellular Neuroscience, 2024 - frontiersin.org
Traumatic brain injury (TBI) is a public health burden affecting millions of people. Sustained
neuroinflammation after TBI is often associated with poor outcome. As a result, increased …
neuroinflammation after TBI is often associated with poor outcome. As a result, increased …
[HTML][HTML] Sex specific effects of buprenorphine on behavior, astrocytic opioid receptor expression and neuroinflammation after pediatric traumatic brain injury in mice
Y Hamood, M Abdullah, H El Ghoul, N Saad… - Brain, Behavior, & …, 2022 - Elsevier
Children who suffered traumatic brain injury (TBI) often experience acute and chronic pain,
which is linked to a poor quality of life. Buprenorphine (BPN) is commonly used to treat …
which is linked to a poor quality of life. Buprenorphine (BPN) is commonly used to treat …
Age-at-injury influences the glial response to traumatic brain injury in the cortex of male juvenile rats
Few translational studies have examined how age-at-injury affects the glial response to
traumatic brain injury (TBI). We hypothesized that rats injured at post-natal day (PND) 17 …
traumatic brain injury (TBI). We hypothesized that rats injured at post-natal day (PND) 17 …
Colony-stimulating factor-1 receptor inhibition transiently attenuated the peripheral immune response to experimental traumatic brain injury
KR Giordano, M Saber, TRF Green… - Neurotrauma …, 2023 - liebertpub.com
To investigate microglial mechanisms in central and peripheral inflammation after
experimental traumatic brain injury (TBI), we inhibited the colony-stimulating factor-1 …
experimental traumatic brain injury (TBI), we inhibited the colony-stimulating factor-1 …