Redox-and non-redox-metal-induced formation of free radicals and their role in human disease

M Valko, K Jomova, CJ Rhodes, K Kuča… - Archives of toxicology, 2016 - Springer
Transition metal ions are key elements of various biological processes ranging from oxygen
formation to hypoxia sensing, and therefore, their homeostasis is maintained within strict …

The diverse role of selenium within selenoproteins: a review

DH Holben, AM Smith - Journal of the American Dietetic Association, 1999 - Elsevier
Selenium functions within mammalian systems primarily in the form of selenoproteins.
Selenoproteins contain selenium as selenocysteine and perform a variety of physiological …

Elevated levels of oxidized low density lipoprotein show a positive relationship with the severity of acute coronary syndromes

S Ehara, M Ueda, T Naruko, K Haze, A Itoh, M Otsuka… - Circulation, 2001 - Am Heart Assoc
Background—There is accumulating data that acute coronary syndromes relate to recent
onset activation of inflammation affecting atherosclerotic plaques. Increased blood levels of …

Macrophage scavenger receptor CD36 is the major receptor for LDL modified by monocyte-generated reactive nitrogen species

EA Podrez, M Febbraio, N Sheibani… - The Journal of …, 2000 - Am Soc Clin Investig
The oxidative conversion of LDL into an atherogenic form is considered a pivotal event in
the development of cardiovascular disease. Recent studies have identified reactive nitrogen …

The curcuma antioxidants: pharmacological effects and prospects for future clinical use. A review

J Miquel, A Bernd, JM Sempere, J Dıaz-Alperi… - Archives of gerontology …, 2002 - Elsevier
In agreement with the predictions of the oxygen-stress theory of aging and age-related
degenerative diseases, diet supplementation with a number of phenolic or thiolic …

Lycopene and myocardial infarction risk in the EURAMIC Study

L Kohlmeier, JD Kark, E Gomez-Gracia… - American Journal of …, 1997 - academic.oup.com
A multicenter case-control study was conducted to evaluate the relations between
antioxidant status assessed by biomarkers and acute myocardial infarction. Incidence cases …

Oxidative stress in vascular dementia and Alzheimer's disease: a common pathology

S Bennett, MM Grant, S Aldred - Journal of Alzheimer's …, 2008 - journals.sagepub.com
Alzheimer's disease and vascular dementia are the two most common types of dementia
with the former being the most predominant. It is evident that oxidative stress, an …

Regulation of enzymatic lipid peroxidation: the interplay of peroxidizing and peroxide reducing enzymes

H Kühn, A Borchert - Free Radical Biology and Medicine, 2002 - Elsevier
For a long time lipid peroxidation has only been considered a deleterious process leading to
disruption of biomembranes and thus, to cellular dysfunction. However, when restricted to a …

Heme oxygenase–carbon monoxide signalling pathway in atherosclerosis: anti-atherogenic actions of bilirubin and carbon monoxide?

RCM Siow, H Sato, GE Mann - Cardiovascular research, 1999 - academic.oup.com
Atherosclerosis is a major contributor to cardiovascular disease, and genetic disorders of
lipoprotein metabolism are recognized risk factors in atherogenesis. The gaseous …

Lycopene, tomatoes, and the prevention of coronary heart disease

AV Rao - Experimental Biology and Medicine, 2002 - journals.sagepub.com
Coronary heart disease (CHD) is one of the primary causes of death in the Western world.
The emphasis so far has been on the relationship between serum cholesterol levels and the …