Paradigms of acute kidney injury in the intensive care setting
Acute kidney injury (AKI) is a heterogeneous clinical syndrome that has multiple aetiologies,
variable pathogenesis and diverse outcomes. However, these heterogeneities are not …
variable pathogenesis and diverse outcomes. However, these heterogeneities are not …
Prevention of acute kidney injury and protection of renal function in the intensive care unit: update 2017: Expert opinion of the Working Group on Prevention, AKI …
M Joannidis, W Druml, LG Forni, ABJ Groeneveld… - Intensive care …, 2017 - Springer
Background Acute kidney injury (AKI) in the intensive care unit is associated with significant
mortality and morbidity. Objectives To determine and update previous recommendations for …
mortality and morbidity. Objectives To determine and update previous recommendations for …
The impact of population ageing on the burden of chronic kidney disease
The burden of chronic kidney disease (CKD) and its risk factors are projected to rise in
parallel with the rapidly ageing global population. By 2050, the prevalence of CKD category …
parallel with the rapidly ageing global population. By 2050, the prevalence of CKD category …
Nicotinamide mononucleotide: a promising molecule for therapy of diverse diseases by targeting NAD+ metabolism
W Hong, F Mo, Z Zhang, M Huang… - Frontiers in cell and …, 2020 - frontiersin.org
NAD+, a co-enzyme involved in a great deal of biochemical reactions, has been found to be
a network node of diverse biological processes. In mammalian cells, NAD+ is synthetized …
a network node of diverse biological processes. In mammalian cells, NAD+ is synthetized …
Nicotinamide mononucleotide, an NAD+ precursor, rescues age-associated susceptibility to AKI in a sirtuin 1–dependent manner
Y Guan, SR Wang, XZ Huang, Q Xie… - Journal of the …, 2017 - journals.lww.com
The rapid growth of an aging population creates challenges regarding age-related diseases,
including AKI, for which both the prevalence and death rate increase with age. The …
including AKI, for which both the prevalence and death rate increase with age. The …
A risk prediction score for acute kidney injury in the intensive care unit
R Malhotra, KB Kashani, E Macedo… - Nephrology Dialysis …, 2017 - academic.oup.com
Background. Acute kidney injury (AKI) is common in critically ill patients and is associated
with high morbidity and mortality. Early identification of high-risk patients provides an …
with high morbidity and mortality. Early identification of high-risk patients provides an …
Acute kidney injury: from diagnosis to prevention and treatment strategies
J Gameiro, JA Fonseca, C Outerelo… - Journal of clinical …, 2020 - mdpi.com
Acute kidney injury (AKI) is characterized by an acute decrease in renal function that can be
multifactorial in its origin and is associated with complex pathophysiological mechanisms. In …
multifactorial in its origin and is associated with complex pathophysiological mechanisms. In …
Prediction and detection models for acute kidney injury in hospitalized older adults
RJ Kate, RM Perez, D Mazumdar… - BMC medical informatics …, 2016 - Springer
Abstract Background Acute Kidney Injury (AKI) occurs in at least 5% of hospitalized patients
and can result in 40–70% morbidity and mortality. Even following recovery, many subjects …
and can result in 40–70% morbidity and mortality. Even following recovery, many subjects …
Predicting mortality of patients with acute kidney injury in the ICU using XGBoost model
J Liu, J Wu, S Liu, M Li, K Hu, K Li - Plos one, 2021 - journals.plos.org
Purpose The goal of this study is to construct a mortality prediction model using the XGBoot
(eXtreme Gradient Boosting) decision tree model for AKI (acute kidney injury) patients in the …
(eXtreme Gradient Boosting) decision tree model for AKI (acute kidney injury) patients in the …
Obesity, acute kidney injury, and mortality in critical illness
Objectives: Although obesity is associated with risk for chronic kidney disease and improved
survival, less is known about the associations of obesity with risk of acute kidney injury and …
survival, less is known about the associations of obesity with risk of acute kidney injury and …