Acetylcholine in the brain alters neuronal excitability, influences synaptic transmission,
induces synaptic plasticity, and coordinates firing of groups of neurons. As a result, it …

Developmental periods such as gestation and adolescence have enhanced plasticity
leaving the brain vulnerable to harmful effects from nicotine use. Proper brain maturation …

Subtypes of neuronal nicotinic acetylcholine receptors (nAChRs) are constructed from
numerous subunit combinations that compose channel-receptor complexes with varied …

Profound Deafness in Childhood | New England Journal of Medicine Skip to main content The
New England Journal of Medicine homepage Advanced Search SEARCH SPECIALTIES …

Nicotinic acetylcholine receptors (nAChRs) regulate critical aspects of brain maturation
during the prenatal, early postnatal, and adolescent periods. During these developmental …

The modern cochlear implant (CI) is the most successful neural prosthesis developed to
date. CIs provide hearing to the profoundly hearing impaired and allow the acquisition of …

Given the rise in teenage use of electronic nicotine delivery systems (“vaping”) in
congruence with the increasing numbers of drug-related emergencies, it is critical to expand …

While the health risks associated with adult cigarette smoking have been well described,
effects of nicotine exposure during periods of developmental vulnerability are often …

The human α7 neuronal nicotinic acetylcholine receptor gene (CHRNA7) is ubiquitously
expressed in both the central nervous system and in the periphery. CHRNA7 is genetically …

Sensory and environmental manipulations affect the development of sensory systems.
Higher-order auditory representations (auditory categories or “objects”) evolve with …