Description Proton pump inhibitors (PPIs) are among the most commonly used medications
in the world. Developed for the treatment and prevention of acid-mediated upper …

Abstract The Japanese Society of Gastroenterology (JSGE) revised the third edition of
evidence-based clinical practice guidelines for peptic ulcer disease in 2020 and created an …

Important progress has been made in the management of Helicobacter pylori infection and
in this fifth edition of the Maastricht Consensus Report, key aspects related to the clinical role …

Background & Aims The purpose of this review is to evaluate the risks associated with long-
term use of proton pump inhibitors (PPIs), focusing on long-term use of PPIs for three …

Peptic ulcer disease continues to be a source of significant morbidity and mortality
worldwide. Approximately two-thirds of patients found to have peptic ulcer disease are …

Non-steroidal anti-inflammatory drugs (NSAIDs) are used commonly but can cause foregut
symptoms, peptic ulcer disease and small bowel enteropathy. Such iatrogenic injury can be …

Abstract The European Society for Clinical and Economic Aspects of Osteoporosis and
Osteoarthritis (ESCEO) published a treatment algorithm for the management of knee …

This guideline presents recommendations for the step-wise management of patients with
overt upper gastrointestinal bleeding. Hemodynamic status is first assessed, and …

Аннотация В 2015 г. экспертами, представляющими различные врачебные ассоциации
России, были разработаны клинические рекомендации «Рациональное применение …

OBJECTIVE: To update evidence for available therapies in the treatment of hip and knee
osteoarthritis (OA) and to examine whether research evidence has changed from 31 …