Prostate cancer genetics: variation by race, ethnicity, and geography

TR Rebbeck - Seminars in radiation oncology, 2017 - Elsevier
Prostate cancer rates vary substantially by race, ethnicity, and geography. These disparities
can be explained by variation in access to screening and treatment, variation in exposure to …

Prostate cancer disparities by race and ethnicity: from nucleotide to neighborhood

TR Rebbeck - Cold Spring Harbor perspectives …, 2018 - perspectivesinmedicine.cshlp.org
Prostate cancer (CaP) incidence, morbidity, and mortality rates vary substantially by race
and ethnicity, with African American men experiencing among the highest CaP rates in the …

TMPRSS2:ERG Gene Fusions in Prostate Cancer of West African Men and a Meta-Analysis of Racial Differences

CK Zhou, D Young, ED Yeboah… - American journal of …, 2017 - academic.oup.com
The prevalence of fusions of the transmembrane protease, serine 2, gene (TMPRSS2) with
the erythroblast transformation-specific–related gene (ERG), or TMPRSS2: ERG, in prostate …

The role of immunohistochemical analysis as a tool for the diagnosis, prognostic evaluation and treatment of prostate cancer: a systematic review of the literature

A Carneiro, ÁRG Barbosa, LS Takemura… - Frontiers in …, 2018 - frontiersin.org
Background: Prostate cancer (PCa) is a heterogeneous disease that lends itself toward
numerous therapeutic options depending on its risk stratification. One of the greatest …

[HTML][HTML] Sex hormones and genetic variants in hormone metabolic pathways associated with the risk of colorectal cancer

S Li, Y Chen, L Xie, Y Meng, L Zhu, H Chu, D Gu… - Environment …, 2020 - Elsevier
Objective The different incidence of colorectal cancer between the sexes suggests that sex
hormones may be involved in the susceptibility to colorectal cancer. The association …

The prognostic value of gender in gastric gastrointestinal stromal tumors: a propensity score matching analysis

J Rong, S Chen, C Song, H Wang, Q Zhao… - Biology of sex …, 2020 - Springer
Abstract Background Gastrointestinal stromal tumors (GISTs) of the stomach are the most
common GISTs. The risk, incidence, and outcome of cancer are different between the sexes …

Inhibition of histamine receptor H3R suppresses prostate cancer growth, invasion and increases apoptosis via the AR pathway

J Chen, XY Hu - Oncology Letters, 2018 - spandidos-publications.com
Histamine h3 receptor (H3R) is expressed in numerous types of tumor and is associated
with tumor cell proliferation, migration and invasion. However, whether H3R is expressed in …

Pre-diagnostic serum metabolomic profiling of prostate cancer survival

J Huang, SJ Weinstein, SC Moore… - The Journals of …, 2019 - academic.oup.com
Impaired metabolism may play a role in the development and lethality of prostate cancer, yet
a comprehensive analysis of the interrelationships appears lacking. We measured 625 …

Height, Obesity, and the Risk of TMPRSS2:ERG-Defined Prostate Cancer

RE Graff, TU Ahearn, A Pettersson, EM Ebot… - … Biomarkers & Prevention, 2018 - AACR
Background: The largest molecular subtype of primary prostate cancer is defined by the
TMPRSS2: ERG gene fusion. Few studies, however, have investigated etiologic differences …

Etiology of prostate cancer with the TMPRSS2:ERG fusion: A systematic review of risk factors

CB McGrath, AH Shreves… - … Journal of Cancer, 2024 - Wiley Online Library
The most common somatic alteration in primary prostate cancer is the TMPRSS2: ERG gene
fusion, which may be caused or promoted by distinct etiologic factors. The objective of this …