Plant cells accumulate small RNA molecules that regulate plant development, genome
stability, and environmental responses. These small RNAs fall into three major classes …

Plant genomes encode various small RNAs that function in distinct, yet overlapping, genetic
and epigenetic silencing pathways. However, the abundance and diversity of small-RNA …

Small-RNA-guided gene regulation has emerged as one of the fundamental principles in
cell function, and the major protein players in this process are members of the Argonaute …

Argonaute proteins are conserved throughout all domains of life. Recently characterized
prokaryotic Argonaute proteins (pAgos) participate in host defense by DNA interference …

In eukaryotic RNA silencing, RNase-III classes of enzymes in the Dicer family process
double-stranded RNA of cellular or exogenous origin into small-RNA (sRNA) molecules …

RNA interference is widely distributed in eukaryotes and has a variety of functions, including
antiviral defence and gene regulation,. All RNA interference pathways use small single …

Since its relatively recent discovery, RNA interference (RNAi) has emerged as a potent,
specific and ubiquitous means of gene regulation. Through a number of pathways that are …

Functions of prokaryotic Argonautes (pAgo) have long remained elusive. Recently,
Argonautes of the bacteria Rhodobacter sphaeroides and Thermus thermophilus were …

Short interfering RNAs (siRNAs) are processed from long double-stranded RNA (dsRNA),
and a guide strand is selected and incorporated into the RNA-induced silencing complex …

Argonaute (AGO) family proteins are effectors of RNAi in eukaryotes. AGOs bind small RNAs
and use them as guides to silence target genes or transposable elements at the …