[HTML][HTML] Spinal cord microglia drive sex differences in ethanol-mediated PGE2-induced allodynia

SN Alexander, OA Reed, MD Burton - Brain, Behavior, and Immunity, 2024 - Elsevier
The mechanisms of how long-term alcohol use can lead to persistent pain pathology are
unclear. Understanding how earlier events of short-term alcohol use can lower the threshold …

The influence of sex on neuroimmune communication, pain, and physiology

SN Alexander, AR Green, EK Debner… - Biology of sex …, 2024 - Springer
Abstract With the National Institutes of Health's mandate to consider sex as a biological
variable (SABV), there has been a significant increase of studies utilizing both sexes …

[HTML][HTML] Pain research in a petri dish? Advantages and limitations of neuro-glial primary cell cultures from structures of the nociceptive system

S Leisengang - Brain, Behavior, & Immunity-Health, 2024 - Elsevier
How can we learn more about pain without causing pain in humans or animals? This short
review focuses on neuro-glial primary cell cultures as models to study neuro-immune …

Long‐lasting mechanical hypersensitivity and CRF receptor type‐1 neuron activation in the BNST following adolescent ethanol exposure

NB Bertagna, L Wilson, CK Bailey… - Alcohol: Clinical and …, 2024 - Wiley Online Library
Background Adolescent alcohol use can produce long‐lasting alterations in brain function,
potentially leading to adverse health outcomes in adulthood. Emerging evidence suggests …

[HTML][HTML] Excessive alcohol intake produces persistent mechanical allodynia and dysregulates the endocannabinoid system in the lumbar dorsal root ganglia of …

V Borgonetti, V Vozella, T Ware, B Cruz… - Pharmacological …, 2024 - Elsevier
Epidemiological data indicate a strong association between alcohol use disorder (AUD) and
neuropathic pain. Genetically-selected Marchigian Sardinian alcohol-preferring (msP) rats …

Within and Beyond the Binary: Sex and Gender Differences in Pain and Alcohol Use Disorder

T Fitzpatrick-Schmidt, S Edwards - Current Addiction Reports, 2024 - Springer
Abstract Purpose of Review Alcohol use disorder (AUD) and chronic pain are frequently
comorbid conditions. This review aims to communicate recent research describing the …

Exploring the Role of Ac1 Inhibition in Pain and Alcohol Reward-Related Behavior in a High Alcohol Preferring Mouse Line

MM Karth - 2024 - search.proquest.com
Previous research shows that the prevalence rates for alcohol use disorder, opioid use
disorder, and chronic pain are high worldwide. Additional work has demonstrated that the …