Radiotherapy (RT) is a cancer treatment that uses high doses of radiation to kill cancer cells
and shrink tumors. Although great success has been achieved on radiotherapy, there is still …

Artemisinins are a family of sesquiterpene trioxane lactone anti-malarial agents originally
derived from Artemisia annua L. The anti-malarial action of artemisinins involves the …

The crosstalk between tumor and stroma cells is a central scenario in the tumor
microenvironment (TME). While the predominant effect of tumor cells on immune cells is …

Improvement of quality of life and survival of cancer patients will be greatly enhanced by the
development of highly effective drugs to selectively kill malignant cells. Artemisinin and its …

Gliomas are malignant tumors in the central nervous system. Cuproptosis is a newly
discovered cell death mechanism targeting lipoylated tricarboxylic acid cycle proteins …

Artemisinins are derived from extracts of sweet wormwood (Artemisia annua) and are well
established for the treatment of malaria, including highly drug-resistant strains. Their efficacy …

Artemisinin contains an endoperoxide moiety that can react with iron to form cytotoxic free
radicals. Cancer cells contain significantly more intracellular free iron than normal cells and …

Artemisinins are a unique class of antimalarial drugs with significant potential for drug
repurposing for a wide range of diseases including cancer. Cancer is a leading cause of …

The world is experiencing a cancer epidemic and an increase in the prevalence of the
disease. Cancer remains a major killer, accounting for more than half a million deaths …

The anti‑malarial drug artemisinin has shown anticancer activity in vitro and animal
experiments, but experience in human cancer is scarce. However, the ability of artemisinins …