Neutrophil extracellular traps and neutrophil-derived extracellular vesicles: Common players in neutrophil effector functions

H Pfister - Diagnostics, 2022 - mdpi.com
Neutrophil granulocytes are a central component of the innate immune system. In recent
years, they have gained considerable attention due to newly discovered biological effector …

Proteomic profiling of the ECM of xenograft breast cancer metastases in different organs reveals distinct metastatic niches

JD Hebert, SA Myers, A Naba, G Abbruzzese… - Cancer research, 2020 - AACR
Metastasis causes most cancer-related deaths, and one poorly understood aspect of
metastatic cancer is the adaptability of cells from a primary tumor to create new niches and …

Meta-analysis of gene expression signatures defining the epithelial to mesenchymal transition during cancer progression

CJ Gröger, M Grubinger, T Waldhör, K Vierlinger… - PloS one, 2012 - journals.plos.org
The epithelial to mesenchymal transition (EMT) represents a crucial event during cancer
progression and dissemination. EMT is the conversion of carcinoma cells from an epithelial …

Proteomics analysis of malignant and benign prostate tissue by 2D DIGE/MS reveals new insights into proteins involved in prostate cancer

K Davalieva, IM Kostovska, S Kiprijanovska… - The …, 2015 - Wiley Online Library
BACKGROUND The key to a more effective diagnosis, prognosis, and therapeutic
management of prostate cancer (PCa) could lie in the direct analysis of cancer tissue. In this …

Infiltrating myeloid cells exert protumorigenic actions via neutrophil elastase

I Lerman, ML Garcia-Hernandez… - Molecular Cancer …, 2017 - AACR
Tissue infiltration and elevated peripheral circulation of granulocytic myeloid-derived cells is
associated with poor outcomes in prostate cancer and other malignancies. Although myeloid …

Comprehensive DNA methylation study identifies novel progression-related and prognostic markers for cutaneous melanoma

J Wouters, M Vizoso, A Martinez-Cardus, FJ Carmona… - BMC medicine, 2017 - Springer
Background Cutaneous melanoma is the deadliest skin cancer, with an increasing
incidence and mortality rate. Currently, staging of patients with primary melanoma is …

[HTML][HTML] PDIA3 modulates genomic response to 1, 25-dihydroxyvitamin D3 in squamous cell carcinoma of the skin

JI Nowak, AM Olszewska, A Piotrowska, K Myszczyński… - Steroids, 2023 - Elsevier
An active form of vitamin D 3 (1, 25-dihydroxyvitamin D 3) acts through vitamin D receptor
(VDR) initiating genomic response, but several studies described also non-genomic actions …

CHD5 inhibits metastasis of neuroblastoma

AK Laut, C Dorneburg, A Fürstberger, TFE Barth… - Oncogene, 2022 - nature.com
CHD5, a tumor suppressor at 1p36, is frequently lost or silenced in poor prognosis
neuroblastoma (NB) and many adult cancers. The role of CHD5 in metastasis is unknown …

piR‐39980 promotes cell proliferation, migration and invasion, and inhibits apoptosis via repression of SERPINB1 in human osteosarcoma

B Das, N Jain, B Mallick - Biology of the Cell, 2020 - Wiley Online Library
Background Information Piwi‐interacting RNAs (piRNAs) are a novel class of∼ 23–36 nts
long endogenous small non‐coding RNAs, earlier known to maintain germline genome …

SERPINB1 promotes Senecavirus A replication by degrading IKBKE and regulating the IFN pathway via autophagy

J Yan, Y Gao, J Bai, J Li, M Li, X Liu, P Jiang - Journal of Virology, 2023 - Am Soc Microbiol
Innate immunity and autophagy play crucial roles in regulating Senecavirus A (SVA)
replication. However, the reciprocal coordination between these systems during virus …