Liver ischaemia–reperfusion injury (LIRI), a local sterile inflammatory response driven by
innate immunity, is one of the primary causes of early organ dysfunction and failure after …

The perspectives of regenerative medicine are still severely hampered by the host response
to biomaterial implantation, despite the robustness of technologies that hold the promise to …

Classically considered short-lived and purely defensive leukocytes, neutrophils are unique
in their fast and moldable response to stimulation. This plastic behavior may underlie …

As one of the first defenders of innate immune response, neutrophils make a rapid and
robust response against infection or harmful agents. While traditionally regarded as suicidal …

Smoking has a profound impact on tumor immunity, and nicotine, which is the major
addictive component of smoke, is known to promote tumor progression despite being a non …

Myocardial infarction is a prevalent major cardiovascular event that arises from myocardial
ischemia with or without reperfusion, and basic and translational research is needed to …

Neutrophils are becoming recognized as highly versatile and sophisticated cells that display
de novo synthetic capacity and potentially prolonged lifespan. Emerging concepts such as …

Heart failure is a consequence of various cardiovascular diseases and associated with poor
prognosis. Despite progress in the treatment of heart failure in the past decades, prevalence …

Neutrophils are the most abundant immune cells in humans and serve as first responders to
a myriad of host perturbations. Equipped with a plethora of antimicrobial molecules …

Neutrophils promptly accumulate in large numbers at sites of tissue injury. Injuries to the skin
or mucosae disrupt barriers against the external environment, and the bactericidal actions of …