Engineered human myocardium with local release of angiogenic proteins improves vascularization and cardiac function in injured rat hearts
Heart regeneration after myocardial infarction requires new cardiomyocytes and a
supportive vascular network. Here, we evaluate the efficacy of localized delivery of …
supportive vascular network. Here, we evaluate the efficacy of localized delivery of …
[HTML][HTML] Peptide Lv and Angiogenesis: A Newly Discovered Angiogenic Peptide
DL Pham, K Cox, ML Ko, GYP Ko - Biomedicines, 2024 - mdpi.com
Peptide Lv is a small endogenous secretory peptide with~ 40 amino acids and is highly
conserved among certain several species. While it was first discovered that it augments L …
conserved among certain several species. While it was first discovered that it augments L …
Peptide Lv Promotes Trafficking and Membrane Insertion of KCa3.1 through the MEK1–ERK and PI3K–Akt Signaling Pathways
DL Pham, A Niemi, R Blank, G Lomenzo, J Tham… - Cells, 2023 - mdpi.com
Peptide Lv is a small endogenous secretory peptide that is proangiogenic through
hyperpolarizing vascular endothelial cells (ECs) by enhancing the current densities of KCa3 …
hyperpolarizing vascular endothelial cells (ECs) by enhancing the current densities of KCa3 …
Decreased microRNA-150 exacerbates neuronal apoptosis in the diabetic retina
F Yu, ML Ko, GYP Ko - Biomedicines, 2021 - mdpi.com
Diabetic retinopathy (DR) is a chronic complication associated with diabetes and the
number one cause of blindness in working adults in the US. More than 90% of diabetic …
number one cause of blindness in working adults in the US. More than 90% of diabetic …
Peptide Lv augments intermediate-conductance calcium-dependent potassium channels (KCa3.1) in endothelial cells to promote angiogenesis
DL Pham, A Niemi, ML Ko, GYP Ko - Plos one, 2022 - journals.plos.org
Peptide Lv is a small endogenous secretory peptide that is expressed in various tissues and
conserved across different species. Patients with diabetic retinopathy, an ocular disease …
conserved across different species. Patients with diabetic retinopathy, an ocular disease …
Patterned Arteriole-Scale Vessels Enhance Engraftment, Perfusion, and Vessel Branching Hierarchy of Engineered Human Myocardium for Heart Regeneration
Heart regeneration after myocardial infarction (MI) using human stem cell-derived
cardiomyocytes (CMs) is rapidly accelerating with large animal and human clinical trials …
cardiomyocytes (CMs) is rapidly accelerating with large animal and human clinical trials …
Newly identified Peptide, Peptide Lv, promotes pathological angiogenesis
Background We recently discovered a small endogenous peptide, peptide Lv, with the ability
to activate vascular endothelial growth factor receptor 2 and its downstream signaling. As …
to activate vascular endothelial growth factor receptor 2 and its downstream signaling. As …
[PDF][PDF] 184. 変形性膝関節症における炎症非依存性の疼痛機序の解明
高野昇太郎 - 2021 - ueharazaidan.or.jp
平成 28 年 10 月現在, 我が国の 65 歳以上の高齢者人口の総人口に占める割合 (高齢化率) は
27.3% となり, 他の国に類をみない超高齢社会を迎えている. 高齢化に伴い変形性膝関節症 (OA) …
27.3% となり, 他の国に類をみない超高齢社会を迎えている. 高齢化に伴い変形性膝関節症 (OA) …