Cancer is one of the major and leading causes of death worldwide. Two of the greatest
challenges in fighting cancer are early detection and effective treatments with no or …

Hyperbranched polymers (HBPs) have found use in a wide range of applications, such as
optical, electronic and magnetic materials, coatings, additives, supramolecular chemistry …

Cabazitaxel, a novel tubulin inhibitor with poor affinity for P-glycoprotein, is a second-
generation taxane holding great promise for the treatment of metastatic castration-resistant …

The surface of a cell represents a collection of macromolecules, which provides the cell with
a unique cellular landscape specific to the type and state of the cell. Ligands that …

Prostate-specific membrane antigen (PSMA), a type II transmembrane metallo-peptidase
highly overexpressed in prostate cancer cells, has been studied as a targeting molecule in …

The objectives of this study were to identify novel peptides from albumin, and to evaluate
and validate the anti-diabetic activity of peptides against α-glucosidase and α-amylase. In …

Heterogeneous expression of drug target proteins within tumor sites is a major mechanism
of resistance to anticancer therapies. We describe a strategy to selectively inhibit, within …

The aim of this study was to search and identify potential anti-diabetic peptides with α-
glucosidase and α-amylase inhibitory activities. After the Alcalase hydrolysis, egg white …

Nanoparticles have been intensely pursued for drug delivery for three decades, but their
delivery efficiency remains low despite numerous innovations in nanoparticle manufacturing …

The importance of modified peptides and proteins for applications in drug discovery, and for
illuminating biological processes at the molecular level, is fueling a demand for efficient …