The nuclear factor-κB (NF-κB) family of transcription factors is activated by canonical and
non-canonical signalling pathways, which differ in both signalling components and …

The non-canonical NF-κB pathway is an important arm of NF-κB signaling that
predominantly targets activation of the p52/RelB NF-κB complex. This pathway depends on …

The noncanonical nuclear factor‐κB (NF‐κB) signaling pathway mediates activation of the
p52/RelB NF‐κB complex and, thereby, regulates specific immunological processes. This …

Post translational modifications (PTMs) are involved in variety of cellular activities and
phosphorylation is one of the most extensively studied PTM, which regulates a number of …

The mammalian Rel/NF-κB family of transcription factors, including RelA, c-Rel, RelB, NF-
κB1 (p50 and its precursor p105), and NF-κB2 (p52 and its precursor p100), plays a central …

A single mouse click on the topic tumor necrosis factor (TNF) in PubMed reveals about 50
000 articles providing one or the other information about this pleiotropic cytokine or its …

Nuclear factor of κB (NF-κB) is a sequence-specific transcription factor that is known to be
involved in the inflammatory and innate immune responses. Although the importance of NF …

NF-κB transcription factors have been suspected to be involved in cancer development
since their discovery because of their kinship with the v-Rel oncogene product. Subsequent …

The transcription factor NF-κB plays a major role in coordinating innate and adaptative
immunity, cellular proliferation, apoptosis and development. Since the discovery in 1991 that …

The nuclear factor kB (NF-kB) comprises a family of transcription factors involved in the
regulation of a wide variety of biological responses. NF-kB plays a well-known function in …